5652-28-8 Usage
Uses
Used in Neuroscience Research:
(+-)-2-AMINO-3-PHOSPHONOPROPIONIC ACID (AP-3)NMDA ANTAGONIST is used as a research tool for studying the role of mGluR in various neurological processes. It helps researchers understand the involvement of these receptors in long-term potentiation in the hippocampus, which is a model of learning and memory.
Used in Parkinson's Disease Research:
In the field of neurodegenerative diseases, (+-)-2-AMINO-3-PHOSPHONOPROPIONIC ACID (AP-3)NMDA ANTAGONIST is used as a research compound to investigate the release of glutamate in Parkinson's disease. This helps in understanding the disease's progression and potential therapeutic targets.
Used in Fragile X Syndrome Research:
(+-)-2-AMINO-3-PHOSPHONOPROPIONIC ACID (AP-3)NMDA ANTAGONIST is utilized as a research agent to study the increased activity of mGluR implicated in fragile X syndrome. This application aids in the development of potential treatments and interventions for this genetic disorder.
Used in Drug Development:
In the pharmaceutical industry, (+-)-2-AMINO-3-PHOSPHONOPROPIONIC ACID (AP-3)NMDA ANTAGONIST is used as a lead compound for the development of new drugs targeting mGluR. This can potentially lead to the creation of novel therapeutics for various neurological and neurodegenerative conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 5652-28-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,6,5 and 2 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 5652-28:
(6*5)+(5*6)+(4*5)+(3*2)+(2*2)+(1*8)=98
98 % 10 = 8
So 5652-28-8 is a valid CAS Registry Number.
5652-28-8Relevant academic research and scientific papers
PREPARATION D'ACIDES AMINOCARBOXY-ALKYLPHOSPHONIQUES OPTIQUEMENT ACTIFS
Villanueva, J. M.,Collignon, N.,Guy, A.,Savignac, Ph.
, p. 1299 - 1306 (2007/10/02)
In aqueous solution ω-formylalkylphosphonates in the presence of hydrogen cyanide and (S) (-) α-methylbenzylamine give optically active aminonitriles with an enantiomeric excess of 50percent.Phosphonic aminonitriles are submitted to acid hydrolysis, then esterified and debenzylated without any epimerization.The separation is performed either with the acid or with the ester.All the operations are monitored by NMR (1H, 13C, 31P) and whenever possible, by GC.
