56526-84-2

Upstream product

• 6138-90-5 trans-geranyl bromide 
• 150965-73-4 methyl 3,5-dibromo-2,4-dimethoxy-6-methylbenzoate 
• 715-33-3 methyl 2,4-dihydroxy-3,5-dibromo-6-methylbenzoate 
• 6110-37-8 methyl 2,4-dimethoxy-6-methylbenzoate 

Downstream Products

• 1044872-25-4 C₃₁H₃₄N₂O₅ 
• 1044872-11-8 C₁₅H₂₁NO₅ 
• 1044872-10-7 C₁₆H₂₃NO₅ 
• 1044870-75-8 3-(4-hydroxy-3,5-dimethylphenyl)-6,8-dimethoxy-7-(morpholinomethyl)isoquinoline-1(2H)-one 

Relevant academic research and scientific papers

COMPOUNDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES

The present disclosure relates to compounds, which are useful for regulating the expression of apolipoprotei? A-I (ApoA-l), and their use for the treatment and prevention of cardiovascular disease and related disease states, including cholesterol- or lipid-related disorders, such as, for example, atherosclerosis.

A general approach for the synthesis of phenolic natural products. Facile syntheses of grifolin and colletochlorins B and D

A general approach is established for the synthesis of phenolic compounds having terpenoid side chains: (1) protection of the phenolic hydroxyls in the aromatic precursor by ether formation, (2) coupling the aromatic part with a terpenoid bromide, and (3) deprotection to regenerate the hydroxyl groups. This strategy was successfully applied to the synthesis of colletochlorins B and D and grifolin. Some of the colletochlorin derivatives were found to inhibit the cell growth of P388.

Aureolic Acid Antibiotics: Synthesis of Naphthocyclobutene Precursors

The use of the dianion of 1,2-dicarbomethoxycyclobutane, a method introduced by Garrett, has been exploited to produce naphthocyclobutenes with methoxy groups in the naphtho moiety.A highly regioselective functionalization of the cyclobutene ring has been