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4-Thiazolidinone, 2-(2-oxo-2-phenylethylidene)-, also known as 2-(2-Oxo-2-phenylethylidene)-4-thiazolidinone, is a chemical compound with the molecular formula C11H9NO2S. It is a derivative of thiazolidinone, a heterocyclic compound containing a sulfur atom and a nitrogen atom in a five-membered ring. This specific compound features a 2-oxo-2-phenylethylidene group attached to the 2-position of the thiazolidinone ring, which contributes to its unique chemical properties. It is an important intermediate in the synthesis of various pharmaceuticals and agrochemicals, particularly those with potential applications in the development of antibiotics, anti-inflammatory agents, and other therapeutic agents. The compound's structure and reactivity make it a valuable building block in organic synthesis, allowing for the creation of a wide range of complex molecules with diverse biological activities.

5653-99-6

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5653-99-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5653-99-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,6,5 and 3 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 5653-99:
(6*5)+(5*6)+(4*5)+(3*3)+(2*9)+(1*9)=116
116 % 10 = 6
So 5653-99-6 is a valid CAS Registry Number.

5653-99-6Relevant academic research and scientific papers

Synthesis and DNase I inhibitory properties of some 4-thiazolidinone derivatives

Kolarevi?, Ana,Ili?, Budimir S.,Koci?, Gordana,D?ambaski, Zdravko,?melcerovi?, Andrija,Bond?i?, Bojan P.

, p. 264 - 274 (2018/09/11)

Twelve new thiazolidinones were synthesized and, together with 41 previously synthesized thiazolidinones,?evaluated for inhibitory activity against deoxyribonuclease I (DNase I) in vitro. Ten compounds inhibited commercial bovine pancreatic DNase I with a

Reactions of transition metal carbonyl anions with 2-(1-bromoalkylidene) thiazolidin-4-ones: Halogenophilic attack or deprotonation

Sazonov,D?ambaski,Shtern,Markovi?,Beletskaya

scheme or table, p. 29 - 33 (2011/02/25)

Bromophilic attack by the transition metal carbonyl anion, [Re(CO) 5]Na (pKa = 21.1), on 2-(1-bromoalkylidene)thiazolidin-4- ones is significantly faster than abstraction of an acidic lactam hydrogen (pKa ～17-18), when the

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