56536-44-8

Usage

General Description

1-(2,4-Dimethyl-1H-imidazol-5-yl)-ethanone is a chemical compound that belongs to the imidazole family. It is a ketone containing a five-membered heterocyclic ring with two methyl groups and an ethanone group attached to the imidazole ring. 1-(2,4-Dimethyl-1H-imidazol-5-yl)-ethanone is commonly used in organic synthesis and pharmaceutical research as a building block for the synthesis of various biologically active molecules. It has also been studied for its potential pharmacological properties, including its antiviral and antifungal activities. Additionally, it is used as a reagent in chemical reactions and as a starting material for the synthesis of more complex organic compounds.

Upstream product

• 52757-00-3 1-Acetyl-2,4-dimethylimidazole 
• 97749-60-5 1-(2,5-Dimethyl-3H-imidazol-4-yl)-ethanol 
• 930-62-1 2,4-Dimethylimidazole 
• 68282-52-0 2,5-Dimethyl-3H-imidazole-4-carbaldehyde 

Downstream Products

• 403793-52-2 1-(2,3,5-trimethyl-3H-imidazol-4-yl)-ethanone 
• 1377837-66-5 4-Isopropoxy-3-[4-(2,3,5-trimethyl-3H-imidazol-4-yl)-thiazol-2-ylamino]-benzenesulfonamide 
• 1415233-58-7 (5-Fluoro-2-methoxy-phenyl)-[4-(2,3,5-trimethyl-3H-imidazol-4-yl)-thiazol-2-yl]-amine 
• 82982-56-7 1-(2,4-dimethyl-5-imidazolyl)-2-bromoethanone 

Relevant academic research and scientific papers

BIS HETEROARYL INHIBITORS OF PRO-MATRIX METALLOPROTEINASE ACTIVATION

This invention relates to thiazole I and its therapeutic and prophylactic uses, wherein the variables A, Q, J, R1, R3, and R5 are defined in the specification. Disorders treated and/or prevented include rheumatoid arthritis.

METHODS OF INHIBITING PRO MATRIX METALLOPROTEINASE ACTIVATION

This invention relates to methods for preventing, treating or ameliorating an MMP9 and/or MMP13 mediated syndrome, disorder or disease comprising administering to a subject in need thereof an effective amount of a compound listed in the examples section of this specification, or a form, composition or medicament thereof. Disorders treated and/or prevented include rheumatoid arthritis.

Imidazotriazines as Potential Antiasthma Agents

By using inhibition of histamine release from antigen-challenged, sensitized human basophils as a means of identifying a potentialy prophylactic drug for the treatment of asthma, a series of substituted imidazotriazines were found, which wer

2-GUANIDINO-4-HETEROARYL-THIAZOLES

A series of 2-guanidino-4-heteroarylthiazoles, wherein the heteroaryl substituent is selected from thiazolyl, triazolyl, imidazolyl, and 2-alkyl, 2-amino and 2-carboxamido derivatives thereof, are disclosed. The novel compounds have activity as antisecretory agents and histamine H 2 antagonists and are useful for the treatment of gastric hyperacidity and peptic ulcers. Also disclosed are pharmaceutical compositions containing the novel compounds of this invention and a method of using the compounds in the treatment of gastric hyperacidity and peptic ulcers. Novel intermediates useful in the preparation of the novel antisecretory compounds are also described.

Process for preparing 1-substituted-6-n-propyl-8-methylimidazo[1,5-d]-as-triazin-4(3H)-ones

This disclosure describes a novel process for the preparation of 1-(lower alkyl)substituted derivatives of 6-n-propyl-8-alkylimidazo[1,5-d]-as-triazin-4(3H)-ones which are useful as anti-asthmatic agents.