68282-52-0

Usage

Uses

Used in Pharmaceutical Industry:
2,5-Dimethyl-1H-imidazole-4-carboxaldehyde is used as a key intermediate in the synthesis of pharmaceuticals, specifically for the production of antifungal drugs, due to its chemical properties that facilitate the creation of effective medicinal compounds.
Used in Corrosion Inhibition:
DMI is used as a corrosion inhibitor, leveraging its chemical structure to protect materials from degradation, thereby extending their service life and improving performance in various applications.
Used in Pesticide Formulation:
In the agricultural sector, 2,5-Dimethyl-1H-imidazole-4-carboxaldehyde is used as a component in pesticide formulations, contributing to the effectiveness of these products in controlling pests and ensuring crop protection.
Used in UV-Curable Coatings:
DMI serves as a photoinitiator in UV-curable coatings, enabling rapid curing under ultraviolet light, which is beneficial for manufacturing processes that require quick drying and high-performance coatings.
Used in Rubber and Plastics Manufacturing:
In the manufacturing of rubber and plastic products, 2,5-Dimethyl-1H-imidazole-4-carboxaldehyde is utilized to enhance the properties of these materials, such as their durability and flexibility, through its reactive and stable nature.
It is important to handle 2,5-Dimethyl-1H-imidazole-4-carboxaldehyde with care, as it can be an irritant to the skin, eyes, and respiratory system, and may cause allergic reactions in some individuals.

InChI:InChI=1/C6H8N2O/c1-4-6(3-9)8-5(2)7-4/h3H,1-2H3,(H,7,8)

Upstream product

• 68283-57-8 (2,5-dimethyl-1⁽³⁾H-imidazol-4-yl)-methanol 
• 108512-06-7 N-(3-methyl-4-isoxazolyl)acetamide 
• 68283-57-8 2,4-dimethyl-5-(hydroxymethyl)imidazole 

Downstream Products

• 856418-36-5 2-(2-(1-benzyl-4-piperidinyl)ethyl)-5,7-dimethyl-1,2-dihydro-3H-imidazo[1,5-c]imidazol-3-one 
• 56536-44-8 1H-5-Acetyl-2,4-dimethylimidazole 

Relevant academic research and scientific papers

IMIDAZOLE COMPOUNDS AND MEDICINAL USE THEREOF

Imidazole compounds represented by general formula (I): wherein each symbol is as defined in the specification, and salts thereof, and a pharmaceutical composition containing same are provided. These compounds are useful in treating the diseases curable based on a hypoglycemic action, and the diseases curable based on a cGMP-PDE inhibitory action, a smooth muscle relaxing action, a bronchodilating action, a vasodilating action, a smooth muscle cell inhibitory action and an allergy inhibitory action.

New synthetic routes to pyrrolo-[1,2-a]- and -[1,2-c]-imidazol-5-ones by flash vacuum pyrolysis

1-Substituted and 1,3-disubstituted pyrrolo[1,2-c]imidazol-5-ones 25-27 have been made in fair to excellent yield by flash vacuum pyrolysis (FVP) of the Meldrum's acid precursors 11-13. FVP of the appropriate propenoate precursor 23, 22 and 18-20 gives pyrrolo[1,2-c]imidazol-5-one 2, pyrrolo[1,2-a]-imidazol-5-one 3 and their 6-methyl derivatives 28-30 respectively in 32-90% yield. The mechanism of the propenoate pyrolyses involves rate determining E to Z isomerisation of the alkene followed by elimination of an alcohol and electrocyclisation to the fused ring products.

Synthesis of 4(5)-Acyl-, 1-Substituted 5-Acyl, and 1-Substituted 4-Acyl-1H-imidazoles from 4-Aminoisoxazoles

4-Aminoisoxazoles can be acylated with a wide variety of activated carboxylic acids.Hydrogenation of the resulting amides gives α-(acylamino)enaminones, which cyclize to 4(5)-acylimidazoles upon treatment with base.This method allows for the synthesis of acylimidazoles with a wide range of substituents at C-2.Utilization of N-substituted 4-aminoisoxazoles in the same sequence of reactions yields 1-substituted 5-acylimidazoles, a substitution pattern not otherwise easily prepared.Treatment of α-(acylamino)enaminones, derived from N-unsubstituted isoxazoles, with primary amines leads to incorporation of the amine at the β-position with concomitant expulsion of ammonia.This sequence efficiently yields 1-substituted and 1,2-disubstituted 4-acylimidazoles but does not give satisfactory yields of 5-substituted 4-acylimidazoles due to steric inhibition of the amine exchange.

Imidazo[1,5-d]-as-triazine-4(3H)-ones and thiones

There is provided substituted imidazo[1,5-d]-as-triazine-4(3H)-ones and substituted imidazo[1,5-d]-as-triazin-4(3H)-thiones useful as inhibitors of the enzyme cyclic-AMP phosphodiesterase and as broad spectrum herbicides.

Method for the control of undesired plant species using imidazo-as-triazinones and triazine-thiones

This disclosure describes herbicidal methods for the pre- and postemergence control of undesired mono- and dicotyledonous plants using substituted imidazo[1,5-d]-as-triazin-4(3H)-ones and substituted imidazo[1,5-d]-as-triazine-4(3H)-thiones.

IMIDAZO [1,5-d]-AS-TRIAZINE-4(3H)-ONES AND THIONES

There is provided substituted imidazo[1,5-d]-as-triazine-4(3H)-ones and substituted imidazo[1,5-d]-as-triazin-4(3H)-thiones useful as inhibitors of the enzyme cyclic-AMP phosphodiesterase and as broad spectrum herbicides

Imidazo[1,5-d]-as-triazines

There are provided novel substituted imidazo-[1,5-d]-as-triazines useful as hypotensive agents as well as exhibiting herbicidal activity.

SUBSTITUTED 3-(4-IMIDAZOLYLMETHYLENE)CARBAZIC AND THIOCARBAZIC ACID ESTERS

There are provided substituted 3-(4-imidazolyl-methylene)carbazic acid esters and 3-(4-imidazolylmethylene)dithiocarbazic acid esters useful as intermediates for the preparation of compounds which inhibit the enzyme cyclic-AMP phosphodiesterase