565462-94-4

Upstream product

• 110-87-2 3,4-dihydro-2H-pyran 
• 453525-11-6 tetrahydropyran-2-yl 2,3,4,6-tetra-O-acetyl-5-deoxy-5-thio-α-D-glucopyranoside 
• 100-39-0 benzyl bromide 
• 453524-96-4 tetrahydropyran-2-yl 5-deoxy-5-thio-α-D-glucopyranoside 
• 137886-82-9 2,3,4,6-Tetra-O-acetyl-5-thio-α-D-glucopyranose 

Downstream Products

• 565462-71-7 2,3,4,6-tetra-O-benzyl-5-deoxy-5-thio-α-D-glucopyranosyl trichloroacetimidate 
• 565462-96-6 (2S,3R,4S,5S,6R)-3,4,5-Tris-benzyloxy-6-benzyloxymethyl-tetrahydro-thiopyran-2-ol 

Relevant academic research and scientific papers

α-selective glycosylation with 5-thioglucopyranosyl donors; Synthesis of an isomaltotetraoside mimic composed of 5-thioglucopyranose units

A general method for α-selective glycosylation with 5-thioglucopyranosyl donors followed by efficient deprotection of the resulting products was developed. This methodology was utilized in the synthesis of an isomaltotetraoside analogue.

Synthetic studies on oligosaccharides composed of 5-thioglucopyranose units

Glycosylation reactions of 5-thioglucopyranosyl trichloroacetimidates bearing ethereal protective groups at the 2-O-position 14-15, and 37 proceed smoothly to give α-glycosides stereoselectively by using a catalytic amount of silyl triflate. This methodol