565470-69-1

Upstream product

• 100-46-9 benzylamine 
• 49568-76-5 3-benzoylquinoxalin-2(1H)-one 
• 1322668-67-6 3-{α-((4-methylphenyl)imino)benzylidene}quinoxalin-2(1H)-one 
• 100-52-7 benzaldehyde 
• 1322668-66-5 3-{α-((2-methylphenyl)imino)benzylidene}quinoxalin-2(1H)-one 
• 565470-73-7 diethyl α-[3-oxo-3,4-dihydroquinoxalin-2(1H)-ylidene]benzylamidophosphate 
• 124831-91-0 3-(α-chlorobenzyl)-1,2-dihydroxyquinoxalin-2-one 
• 847552-57-2 3-(α-benzylaminobenzyl)quinoxalin-2-one 

Downstream Products

• 1235547-95-1 5-(3-chloroprop-1-yl)-1,3-diphenylimidazo[1,5-a]quinoxalin-4-one 
• 1235547-96-2 4-(3-chloroprop-1-yloxy)-1,3-diphenylimidazo[1,5-a]quinoxaline 
• 1235547-99-5 5-(6-chlorohex-1-yl)-1,3-diphenylimidazo[1,5-a]quinoxalin-4-one 
• 1235547-97-3 5-(6-hydroxyhex-1-yl)-1,3-diphenylimidazo[1,5-a]quinoxalin-4-one 
• 1235547-98-4 1-(1,3-diphenylimidazo[1,5-a]quinoxalin-4-yloxy)-6-(4-oxo-1,3-diphenylimidazo[1,5-a]quinoxalin-5-yl)hexane 

Relevant academic research and scientific papers

A simple and efficient method for the synthesis of highly substituted imidazoles using 3-aroylquinoxalin-2(1H)-ones

3-Aroylquinoxalin-2(1H)-ones were found to be hetero analogues of α-diketones for the efficient, one-pot, three component synthesis of 2,4,5-trisubstituted imidazoles and imidazo[1,5-a]quinoxalin-4(5H)-ones in boiling methanol. The key advantages of this process are high yields, ready availability and low cost of 3-aroylquinoxalin-2(1H)-ones and easy work-up and separation of the products by non-chromatographic methods. Furthermore, the presence of an ortho-iminoanilide fragment at position 4 of the imidazoles obtained has made it possible to produce 2-(imidazol-4-yl)benzimidazoles in almost quantitative yields.

Fused polycyclic nitrogen-containing heterocycles: IX. Oxidative fusion of imidazole ring to 3-benzoylquinoxalin-2-ones

3-α-Chlorobenzyl- and 3-benzoylquinoxalin-2-ones react with benzylamine in DMSO to give intermediate 3-(α-benzyliminobenzylidene) quinoxalin-2-one which is capable of existing in several tautomeric forms. The subsequent oxidative cyclocondensation leads to imidazo[1,5-a]quinoxalin-4-one. This new procedure for building up imidazo[1,5-a]quinoxalin-4-one system has been applied to the synthesis of various bis(imidazo[1,5-a]quinoxalin-4-ones).

Fused Nitrogen-Containing Heterocycles: III. 4-Oxo-1-phenyl-4,5- dihydroimidazo[1,5-a]quinoxalines. A Retrosynthetic Approach

Retrosynthetic analysis of the structure of imidazo[1,5-a]quinoxalines made it possible to develop new convenient procedures for preparation of these compounds by reaction of 3-(α-chlorobenzyl)-1,2-dihydroquinoxalin-2-one with potassium thiocyanate or isocyanate as synthetic equivalent of the two-membered N-=C+ building blocks and by reaction of 3-(α-aminobenzyl)-1,2-dihydroquinoxalin-2-one with carbon disulfide, triethoxymethane, aromatic aldehydes, or acetic anhydride as synthetic equivalent of the one-membered RC3+ synthon.