56612-25-0

Basic information

• Product Name: L-Phenylalanine, N-L-phenylalanyl-, methyl ester, mono(trifluoroacetate)
• CAS NO: 56612-25-0
• Molecular Formula: C19H22N2O3.C2HF3O2
• Molecular Weight: 440.419
• Mol File: 56612-25-0.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: L-Phenylalanine, N-L-phenylalanyl-, methyl ester, mono(trifluoroacetate)(CAS DataBase Reference)
• NIST Chemistry Reference: L-Phenylalanine, N-L-phenylalanyl-, methyl ester, mono(trifluoroacetate)(56612-25-0)
• EPA Substance Registry System: L-Phenylalanine, N-L-phenylalanyl-, methyl ester, mono(trifluoroacetate)(56612-25-0)

Safety Data

• Hazardous Substances Data: 56612-25-0(Hazardous Substances Data)

Upstream product

• 63-91-2 L-phenylalanine 
• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 
• 17585-69-2 L-phenylalanine hydrochloride 
• 7524-50-7 methyl (2S)-2-amino-3-phenylpropanoate hydrochloride 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 13122-89-9 (S)-methyl 2-((S)-2-(tert-butoxycarbonylamino)-3-phenylpropanamido)-3-phenylpropanoate 
• 76-05-1 trifluoroacetic acid 

Downstream Products

• 1365260-17-8 N-Boc-Pro(4(S)-NH(Cbz))-Phe-Phe-OMe 
• 1365260-25-8 TFA*Tyr-cyclo(4(S)-NH-Pro-Phe-Phe) 
• 1365260-27-0 TFA*Pro(4S-NH(Cbz))-Phe-Phe-OMe 
• 1365260-28-1 Cbz-Tyr-Pro(4(S)-NH(Cbz))-Phe-Phe-OMe 
• 1365260-29-2 Cbz-Tyr-Pro(4(S)-NH(Cbz))-Phe-Phe-OH 
• 1365260-31-6 Cbz-Tyr-Pro(4S-NH(Cbz))-Phe-Phe-NH₂ 
• 1365260-18-9 N-Boc-Pro(4(S)-NH(Cbz))-Phe-Phe-OH 
• 1365260-19-0 N-Boc-Pro(4(S)-NH₂)-Phe-Phe-OH 
• 1471520-00-9 N-Boc-Tyr-Pro-Phe-Phe-OMe 
• 1471520-10-1 N-Boc-Tyr-Pro-Phe-Phe-NH(CH₂)₂OH 
• 1471520-22-5 TFA·Tyr-Pro-Phe-Phe-NH(CH₂)₂OH 

Relevant articles and documents

A Comprehensive Landscape for Fibril Association Behaviors Encoded Synergistically by Saccharides and Peptides

Nature provides us a panorama of fibrils with tremendous structural polymorphism from molecular building blocks to hierarchical association behaviors. Despite recent achievements in creating artificial systems with individual building blocks through self-

Tricomponent Supramolecular Multiblock Copolymers with Tunable Composition via Sequential Seeded Growth

Synthesis of supramolecular block co-polymers (BCP) with small monomers and predictive sequence requires elegant molecular design and synthetic strategies. Herein we report the unparalleled synthesis of tri-component supramolecular BCPs with tunable microstructure by a kinetically controlled sequential seeded supramolecular polymerization of fluorescent π-conjugated monomers. Core-substituted naphthalene diimide (cNDI) derivatives with different core substitutions and appended with β-sheet forming peptide side chains provide perfect monomer design with spectral complementarity, pathway complexity and minimal structural mismatch to synthesize and characterize the multi-component BCPs. The distinct fluorescent nature of various cNDI monomers aids the spectroscopic probing of the seeded growth process and the microscopic visualization of resultant supramolecular BCPs using Structured Illumination Microscopy (SIM). Kinetically controlled sequential seeded supramolecular polymerization presented here is reminiscent of the multi-step synthesis of covalent BCPs via living chain polymerization. These findings provide a promising platform for constructing unique functional organic heterostructures for various optoelectronic and catalytic applications.

Silica covering driven intensity enhancement and handedness inversion of the CPL signals of the supramolecular assemblies

A pair of Phe-Phe dipeptides with a tolane group were synthesized by introducing tolane with high emission efficiency to phenylalanine dipeptide. The sodium salts of the dipeptides were able to self-assemble into straight belts in a mixture of methanol and water. The supramolecular assemblies exhibited circularly polarized luminescence (CPL) properties. They can be used as templates to prepare dipeptide-based hybrid silicas through a supramolecular templating approach. The hybrid materials formed coiled nanoribbons, which showed a distinct and different morphology compared to supramolecular assemblies. Moreover, since silica covering can affect the packing structures of the tolane groups, the intensity of the CPL was enhanced and its handedness was inversed. This journal is