56636-93-2

Upstream product

• 1493-27-2 ortho-nitrofluorobenzene 
• 156-87-6 propan-1-ol-3-amine 
• 88-73-3 2-Chloronitrobenzene 

Downstream Products

• 62781-00-4 1-(3-chloropropyl)2-nitroaniline 
• 213118-61-7 1-(2-Amino-phenyl)-1-(3-hydroxy-propyl)-3-methyl-urea 
• 99179-96-1 N-(3-bromo-propyl)-2-nitro-aniline 
• 65214-43-9 3-((2-aminophenyl)amino)propan-1-ol 

Relevant academic research and scientific papers

A synthetic route to 3-(heteroaryl)-7-hydroxycoumarins designed for biosensing applications

A straightforward method to synthesize 3-(2-benzimidazolyl)-7-hydroxycoumarins, based on the condensation reaction of 7-acetoxy-3-formylcoumarin with various C-and/or Nsubstituted ortho-phenylenediamine derivatives is presented. This unusual approach prov

BENZIMIDAZOLECARBOXAMIDES AS INHIBITORS OF FAK

This invention relates to benzimadolecarboxamides of formula (I) which are inhibitors of focal adhesion kinase, and as such are useful for treating proliferative diseases

Synthesis and stability of 5-, 7- and 8-substituted benzo-1,2,3,5-tetrazepin-4-ones

In order to determine the effect of substituents on the stability of benzo-fused 1,2,3,5-tetrazepin-4-ones, 5-, 7- and 8-substituted derivatives (6a-d), and (10) were synthesized. The stability of the tetrazepinones increased with the electron withdrawing character of the substituents at the benzene ring. Bulky groups at the 5 position destabilize the tetrazepinone ring. The unstable tetrazepinones (6b, 10 and 14) decomposed in chloroform at room temperature to benzotriazole derivatives (11, 12 and 15). X-Ray diffraction of nitrobenzotetrazepinone (6d) showed that despite the elctron withdrawing effect of the nitro group para to the triazene chain, N3 exhibited a significant pyramidal character. In 6d, the 1,2,3,5-tetrazepinone cycle has an almost perfect seven-membered ring boat shape.