56680-31-0

Upstream product

• 159862-03-0 (Z)-3-(2-(4-methoxyphenyl)-2-oxoethylidene)indolin-2-one 
• 75-36-5 acetyl chloride 
• 91-56-5 indole-2,3-dione 
• 574-17-4 1-acetyl-1H-indole-2,3-dione 
• 1777-55-5 (4-methoxyphenacylidene)triphenyl phosphorane 
• 56680-33-2 (E)-3-(2-(4-methoxyphenyl)-2-oxoethylidene)indolin-2-one 

Downstream Products

• 56680-46-7 1-acetyl-3-[5-ethoxy-2-(4-methoxy-phenyl)-4,5-dihydro-furan-3-yl]-1,3-dihydro-indol-2-one 
• 71307-29-4 9-acetyl-2-ethoxy-4-(4-methoxy-benzoyl)-9H-pyrano[2,3-b]indole 
• 159862-03-0 (Z)-3-(2-(4-methoxyphenyl)-2-oxoethylidene)indolin-2-one 

Relevant academic research and scientific papers

Cinchona-based squaramide-catalysed cascade aza-Michael-Michael addition: Enantioselective construction of functionalized spirooxindole tetrahydroquinolines

An efficient enantioselective cascade aza-Michael-Michael addition reaction catalysed by a chiral bifunctional tertiary amine-squaramide catalyst has been developed. This cascade reaction proceeded well under mild conditions, furnishing highly functionalized spirooxindole tetrahydroquinolines with three contiguous stereocenters in excellent yields with excellent diastereoselectivities (>25:1 dr) and high enantioselectivities (up to 94% ee). The Royal Society of Chemistry 2013.

An easy Lewis acid-mediated isomerization from (E)- to (Z)-oxoindolin-3-ylidene ketones

(E)-2-Oxoindolin-3-ylidene ketones can be easily isomerized to their (Z)-isomers by AlCl3 at room temperature in CH2Cl2. The behaviour of the unsaturated dicarbonyl framework in the (Z)-configuration as a bidentate ligand