566943-99-5 Usage
General Description
6-Isoquinolinamine,5-chloro-(9CI) is a chemical compound with the molecular formula C9H7ClN2. It belongs to the isoquinolinamine class of compounds and contains a chlorine atom. This chemical is often used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. It has potential applications in drug discovery and development due to its structural features. Additionally, it may have biological activities and properties that can be explored for various research purposes. Its specific chemical and physical properties make it a valuable tool for researchers in the field of medicinal and organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 566943-99-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,6,6,9,4 and 3 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 566943-99:
(8*5)+(7*6)+(6*6)+(5*9)+(4*4)+(3*3)+(2*9)+(1*9)=215
215 % 10 = 5
So 566943-99-5 is a valid CAS Registry Number.
566943-99-5Relevant articles and documents
Identification of novel and potent isoquinoline aminooxazole-based IMPDH inhibitors
Chen, Ping,Norris, Derek,Haslow, Kristin D.,Dhar, T. G. Murali,Pitts, William J.,Watterson, Scott H.,Cheney, Daniel L.,Bassolino, Donna A.,Fleener, Catherine A.,Rouleau, Katherine A.,Hollenbaugh, Diane L.,Townsend, Robert M.,Barrish, Joel C.,Iwanowicz, Edwin J.
, p. 1345 - 1348 (2007/10/03)
Screening of our in-house compound collection led to the discovery of 5-bromo-6-amino-2-isoquinoline 1 as a weak inhibitor of IMPDH. Subsequent optimization of 1 afforded a series of novel 2-isoquinolinoaminooxazole-based inhibitors, represented by 17, with single-digit nanomolar potency against the enzyme.
