566943-99-5 Usage
Uses
Used in Pharmaceutical Synthesis:
6-Isoquinolinamine,5-chloro-(9CI) is used as an intermediate in the synthesis of various pharmaceuticals and organic compounds. Its unique structure and functional groups contribute to the development of new drugs and therapeutic agents.
Used in Drug Discovery and Development:
Due to its structural features, 6-Isoquinolinamine,5-chloro-(9CI) is employed as a starting material or building block in drug discovery and development processes. It aids researchers in designing and optimizing new molecules with potential therapeutic effects.
Used in Medicinal Chemistry Research:
6-Isoquinolinamine,5-chloro-(9CI) is utilized in medicinal chemistry research to explore its biological activities and properties. Its potential applications in this field can lead to the discovery of new compounds with therapeutic relevance.
Used in Organic Chemistry Research:
As a valuable tool for researchers in the field of organic chemistry, 6-Isoquinolinamine,5-chloro-(9CI) is used to study its chemical and physical properties. This knowledge can contribute to the advancement of organic synthesis methods and the development of novel organic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 566943-99-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,6,6,9,4 and 3 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 566943-99:
(8*5)+(7*6)+(6*6)+(5*9)+(4*4)+(3*3)+(2*9)+(1*9)=215
215 % 10 = 5
So 566943-99-5 is a valid CAS Registry Number.
566943-99-5Relevant academic research and scientific papers
Identification of novel and potent isoquinoline aminooxazole-based IMPDH inhibitors
Chen, Ping,Norris, Derek,Haslow, Kristin D.,Dhar, T. G. Murali,Pitts, William J.,Watterson, Scott H.,Cheney, Daniel L.,Bassolino, Donna A.,Fleener, Catherine A.,Rouleau, Katherine A.,Hollenbaugh, Diane L.,Townsend, Robert M.,Barrish, Joel C.,Iwanowicz, Edwin J.
, p. 1345 - 1348 (2007/10/03)
Screening of our in-house compound collection led to the discovery of 5-bromo-6-amino-2-isoquinoline 1 as a weak inhibitor of IMPDH. Subsequent optimization of 1 afforded a series of novel 2-isoquinolinoaminooxazole-based inhibitors, represented by 17, with single-digit nanomolar potency against the enzyme.
