566947-53-3Relevant academic research and scientific papers
7-Oxo-4,7-dihydrothieno[3,2-b]pyridine-6-carboxamides: Synthesis and biological activity of a new class of highly potent inhibitors of human cytomegalovirus DNA polymerase
Larsen, Scott D.,Zhang, Zhijun,DiPaolo, Brian A.,Manninen, Peter R.,Rohrer, Douglas C.,Hageman, Michael J.,Hopkins, Todd A.,Knechtel, Mary L.,Oien, Nancee L.,Rush, Bob D.,Schwende, Francis J.,Stefanski, Kevin J.,Wieber, Janet L.,Wilkinson, Karen F.,Zamora, Kathyrn M.,Wathen, Michael W.,Brideau, Roger J.
, p. 3840 - 3844 (2008/02/10)
We report a new class of non-nucleoside antivirals, the 7-oxo-4,7-dihydrothieno[3,2-b]pyridine-6-carboxamides, some of which possess remarkable potency versus a broad spectrum of herpesvirus DNA polymerases and excellent selectivity compared to human DNA
