56703-54-9Relevant academic research and scientific papers
Application of a tandem seleno-michael/aldol reaction in the total syntheses of (+)-Pericosine B, (+)-Pericosine C, (+)-COTC and 7-chloro-analogue of (+)-Gabosine C
Banachowicz, Piotr,Bidu?, Natalia,Buda, Szymon
, (2020)
Synthesis of (+)-Pericosine B, (+)-Pericosine C, (+)-COTC and a 7-chloro-analogue of (+)-Gabosine C was achieved via tandem seleno-Michael/aldol reactions as key steps. The carbasugar linear precursor was obtained from cheap and readily available D-ribose in 7 steps which included resolution of the D-ribopyranose and the D-ribofuranose forms. Further transformation of the cyclic product involving a regioselective Steglich esterification or methylation of the secondary hydroxyl group gave rise to protected (+)-COTC, (+)-Pericosine B and (+)-Pericosine C. Deprotection of benzyl ethers at ?78 °C gave the titled compounds in satisfactory yields.
Synthesis of imidazole C1- and C3-ribonucleoside phosphoramidites for probing catalytic mechanism in ribozyme
Harusawa, Shinya,Fujii, Kensuke,Nishiura, Masayoshi,Araki, Lisa,Usami, Yoshihide,Zhao, Zheng-Yun,Lilley, David M.J.
scheme or table, p. 2041 - 2055 (2011/10/18)
Synthesis of C4-linked imidazole N-pivaloyloxymethyl (POM)-2'-O- cyanoethylated (CE) C1- and C3-ribonucleoside phosphoramidites 1a and 1b is described. These phosphoramidite products were incorporated into RNA sequence through solid phase phosphoramidite
