56705-51-2

Usage

Uses

Used in Pharmaceutical Industry:
4-(3-Chlorophenoxy)benzamide is used as an intermediate in the synthesis of other chemicals and pharmaceuticals for its potential to contribute to the development of new medications.
Used in Agrochemical Industry:
4-(3-Chlorophenoxy)benzamide is used as a building block in the production of insecticides, herbicides, and fungicides, leveraging its chemical properties to enhance the effectiveness of these agricultural chemicals.
Used in Cancer Research:
4-(3-Chlorophenoxy)benzamide is studied as a potential anti-cancer agent due to its ability to inhibit certain cellular processes, indicating its potential in the development of new therapeutic approaches against cancer. However, further research is required to fully explore and understand its medicinal applications.

InChI:InChI=1/C12H10ClNO/c13-9-2-1-3-12(8-9)15-11-6-4-10(14)5-7-11/h1-8H,14H2

Upstream product

• 586-78-7 para-nitrophenyl bromide 
• 350-46-9 4-Fluoronitrobenzene 
• 108-43-0 3-monochlorophenol 
• 2303-23-3 1-chloro-3-(4-nitrophenoxy)benzene 

Downstream Products

• 57215-69-7 Sodium; 2-chloro-3-[4-(3-chloro-phenoxy)-phenyl]-propionate 
• 1613336-68-7 N-(4-(3-chlorophenoxy)phenyl)-2-hydroxy-3,5-diiodobenzamide 
• 1609355-73-8 C₂₂H₁₈Cl₂N₂O₅S 
• 1609355-72-7 C₂₂H₁₈Cl₂N₂O₄S 
• 1221878-78-9 (S)-2-(2-(1H-imidazol-5-yl)acetamido)-3-(benzyloxy)-N-(4-(3-chlorophenoxy)phenyl)propanamide 
• 1222196-48-6 (S)-2-amino-3-benzyloxy-N-(4-(3-chlorophenoxy)phenyl)propanamide 
• 120848-90-0 2-Chloro-3-[4-(3-chloro-phenoxy)-phenyl]-propionic acid 
• 57181-40-5 2-Chloro-3-[4-(3-chloro-phenoxy)-phenyl]-propionic acid ethyl ester 

Relevant academic research and scientific papers

Synthesis and biological evaluation of pentanedioic acid derivatives as farnesyltransferase inhibitors

Structure-based virtual screening of a commercial library identified pentanedioic acid derivatives (6 and 13b) as a kind of novel scaffold farnesyltransferase inhibitors (FTIs). Chemical modifications of the lead compounds, biological assays and analysis of the structure-activity relationships (SAR) were conducted to discover more potent FTIs. Some of them displayed excellent inhibition against FTase, and among them, the most active compound 13n with an IC50 value of 0.0029 μM and SAR analysis might be helpful to the discovery of more potent FTIs. This journal is

TRIAZOLES AS KV3 INHIBITORS

Compounds of formula (I) are of use in the modulation of Kv3.1, Kv.3.2 and Kv3.3 channels and have utility in the treatment or prevention of related disorders.

Inhibitors of protein kinases

Compounds that inhibit protein kinases, compositions containing the compounds and methods of treating diseases using the compounds are disclosed.

Derivatives of quinoline as inhibitors for MEK

1. A compound of formula (I) or a pharmaceutically acceptable salt thereof. wherein: n is 0-1; X and Y are independently selected from -NH-, -O-, -S-, or -NR8- where R8 is alkyl of 1-6 carbon atoms and X may additionally comprise a CH2 group; R7 is a group (CH2)mR9 where m is 0,or an integer of from 1-3 and R9 is a substituted aryl group, an optionally substituted cycloalkyl ring of up to 10 carbon atoms, or an optionally substituted heterocyclic ring or an N-oxide of any nitrogen containing ring; R6 is a divalent cycloalkyl of 3 to 7 carbon atoms, which may be optionally further substituted with one or more alkyl of 1 to 6 carbon atom groups; or is a divalent pyridinyl, pyimidinyl, or phenyl ring; wherein the pyridinyl, pyrimidinyl, or phenyl ring may be optionally further substituted with one or more specified groups; R1, R2, R3 and R4 are each independently selected from hydrogen or various specified organic groups. Compounds are useful as pharmaceuticals for the inhibition of MEK activity.