56720-91-3Relevant academic research and scientific papers
One-pot Hofmann elimination-transesterification/amidation reactions on REM resin using perfluorous solvents
Morphy, J.Richard,Rankovic, Zoran,York, Mark
, p. 6413 - 6415 (2002)
The incorporation of 2,2,2-trifluoroethanol esters into substrates for the REM resin synthesis of 3° amines allows a one-pot Hofmann elimination/transesterification protocol to be performed. In this way α-amino acid esters and amides were synthesised by a
Reagent concentration effects in the REM resin solid phase synthesis of tertiary amines
Morphy, J. Richard,Rankovic, Zoran,York, Mark
, p. 2137 - 2145 (2007/10/03)
The use of reagent concentration has resulted in increased rates for all stages of the REM resin synthesis of tertiary amines. These increases in rate translate into faster reaction times, higher yields and lower reagent consumption. Of the methods examin
