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Usage

Uses

Used in Personal Care Products:
Triclosan is used as an antimicrobial agent in personal care products such as soaps, toothpaste, and deodorants for its ability to prevent the growth of bacteria and fungi, thereby promoting better hygiene and reducing the risk of infections.
Used in Household Cleaning Products:
In household cleaning products, triclosan is utilized as a preservative and disinfectant to inhibit microbial growth, ensuring the cleanliness and safety of the products and surfaces they are used on.
Used in Medical Devices:
Triclosan is also employed in the manufacturing of certain medical devices as an antimicrobial agent to prevent bacterial colonization and reduce the risk of infection during medical procedures.
However, it is important to note that the use of triclosan has been a subject of controversy due to its potential negative environmental impact and concerns about contributing to antibacterial resistance. Consequently, its use in consumer products has been restricted in some countries, and ongoing research is being conducted to assess its safety and explore potential alternatives.

Upstream product

• 50-00-0 formaldehyd 
• 124-40-3 dimethyl amine 
• 120-83-2 2,4-dichlorophenol 

Downstream Products

• 100865-81-4 3-(3,5-dichloro-2-hydroxy-phenyl)-1-phenyl-propan-1-one 
• 109047-56-5 3-(3,5-dichloro-2-hydroxy-phenyl)-propionic acid 
• 50366-77-3 2,4-Dichloro-6-(toluene-4-sulfonylmethyl)-phenol 
• 50366-78-4 2,4-Dichloro-6-(4-chloro-benzenesulfonylmethyl)-phenol 
• 1022250-17-4 1-(3,5-dichloro-2-{[4-chloro-7-(1-ethylpropyl)-1-methyl-1H-benzimidazol-2-yl]oxy}phenyl)-N,N-dimethylmethanamine 
• 1022249-99-5 1-(3,5-dichloro-2-{[7-(1-ethylpropyl)-4-methoxy-1-methyl-1H-benzimidazol-2-yl]oxy}phenyl)-N,N-dimethylmethanamine 
• 50366-76-2 2-Benzenesulfonylmethyl-4,6-dichloro-phenol 
• 100726-66-7 2-anilinomethyl-4,6-dichloro-phenol 

Relevant academic research and scientific papers

Pyridine phenyl coupling compound and pharmaceutical composition and application thereof

The invention discloses a pyridine phenyl coupling compound and a pharmaceutical composition and application thereof. The pyridine phenyl coupling compound is a PSD-95-nNOs uncoupling agent, can selectively inhibit combination between PSD-95 and nNOs to a

Convenient synthesis of 2-Amino-4H-chromenes from photochemically generated o-quinone methides and malononitrile

2-Amino-4H-chromenes were synthesized in moderate to good yields by the reaction of o-quinone methides photochemically generated from o-(dimethylaminomethyl)phenols with malononitrile. This method was applicable to the synthesis of fluorinated chromenes that were difficult to obtain by other methods. In addition, o-(hydroxymethyl)phenols could be used for the reaction in the presence of tertiary amine bases.

BENZIMIDAZOLE COMPOUNDS

There is provided a compound of the formula (1) wherein R1 is an optionally substituted C1-10 alkyl; R2 is H, or a C1-6 alkyl which may be substituted with 1 to 3 substituents; R3 is a 5- or 6-membered aromatic group which may be substituted with 1 to 5 substituents, wherein the 5- or 6-membered aromatic group may be fused with a 5- or 6- membered ring which may be substituted with 1 to 3 C1-6 alkyls; R4 is a hydrogen, a halogen, a hydroxy, a cyano, a C1-6 alkyl or a C1-6 alkoxy; Z is -O-, -S-, -SO-, -SO2-, or - NR5- wherein R5 is a hydrogen or a C1-6 alkyl; or a salt thereof or a prodrug thereof, which have CRF receptor antagonist activity and use thereof.

Heterocyclic Spirocyclohexadienones from Substituted Phenols

Mannich bases were prepared from substituted phenols with aliphatic amines and formaldehyde.Amine exchange with N-methyl-2-naphthylamine followed by a Hofmann Martius rearrangement gave rise to o,o'-amino-hydroxy-diphenylmethane derivatives.Under cyclization conditions some of these compounds produced spirocyclohexadienones, which are the ipso analogs to the hypothetic intermediates postulated in the aminomethylation mechanism of phenols. - Keywords: Mannich Reaction; Phenol Dienone Tautomerism; Hofmann Martius Rearrangement