56761-29-6Relevant articles and documents
Amidino derivatives and their use as thrombin inhibitors
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, (2008/06/13)
There is provided compounds of formula I, wherein R1, Rx, Y, Ry, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.