56766-92-8Relevant academic research and scientific papers
Fluorine-substituted diphenylethane compound and preparation method and application thereof
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Paragraph 0041; 0042; 0054; 0056-0058; 0063-0066, (2019/10/01)
The invention relates to a fluorine substituted diphenylethane compound, which is characterized in that the structure is shown as a general formula (I): wherein R1 is methyl or ethyl; R2 is hydrogen or fluorine; and R is hydrogen, hydroxyl, benzyloxy, pho
Synthesis and biological evaluation of 2,3-diarylthiophene analogues of combretastatin A-4
Wang, Zhan,Yang, Qingkun,Bai, Zhaoshi,Sun, Jun,Jiang, Xuewei,Song, Hongrui,Wu, Yingliang,Zhang, Weige
supporting information, p. 971 - 976 (2015/05/27)
A series of novel 2,3-diarylthiophene analogues of combretastatin A-4 (CA-4) were designed with a rigid thiophene moiety to retain the cis-olefin configuration of CA-4 and were subsequently synthesised. All of the target compounds were evaluated for their
Synthesis and cytotoxic activities of 4,5-diarylisoxazoles
Sun, Chang-Ming,Lin, Lee-Gin,Yu, Hsi-Jung,Cheng, Chih-Yu,Tsai, Ya-Chuan,Chu, Chi-Wei,Din, Yi-Hui,Chau, Yat-Pang,Don, Ming-Jaw
, p. 1078 - 1081 (2007/10/03)
A series of 4,5-diarylisoxazoles related to combretastatin A-4 (CA-4) were synthesized and evaluated for cytotoxicity against three human cancer cell lines. Among them, compound 6e showed better cytotoxic activity than CA-4 in HeLa and HepG2 cell lines as
