5677-84-9

Basic information

• Product Name: 1,4,5-trimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one
• Synonyms: 1,4,5-Trimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one; 3H-pyrazol-3-one, 1,2-dihydro-1,4,5-trimethyl-2-phenyl-
• CAS NO: 5677-84-9
• Molecular Formula: C₁₂H₁₄N₂O
• Molecular Weight: 202.2524
• Mol File: 5677-84-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 292.5°C at 760 mmHg
• Flash Point: 117.3°C
• Density: 1.118g/cm³
• Vapor Pressure: 0.00183mmHg at 25°C
• Refractive Index: 1.569
• CAS DataBase Reference: 1,4,5-trimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4,5-trimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one(5677-84-9)
• EPA Substance Registry System: 1,4,5-trimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one(5677-84-9)

Safety Data

• Hazardous Substances Data: 5677-84-9(Hazardous Substances Data)

Upstream product

• 60-80-0 antipyrine 
• 74-88-4 methyl iodide 
• 609-14-3 2-acetylpropanoic acid ethyl ester 
• 100-63-0 phenylhydrazine 
• 622-36-6 1-methyl-2-phenylhydrazine 
• 50-00-0 formaldehyd 
• 7713-77-1 4,5-dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-one 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 98395-59-6 1-Methoxymethyl-4,5-dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-one 
• 60473-57-6 3-Bromomethyl-2,4-dimethyl-1-phenyl-3-pyrazolin-5-on 
• 125689-41-0 4,5-bis-diethylaminomethyl-1-methyl-2-phenyl-1,2-dihydro-pyrazol-3-one 
• 110249-92-8 1-methyl-2,5-diphenyl-1,4,5,6-tetrahydro-2H-pyrrolo[3,4-c]pyrazol-3-one 

Relevant articles and documents

PYRAZOLONE COMPOUNDS AS METABOTROPIC GLUTAMATE RECEPTOR AGONISTS FOR THE TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS

Compounds of Formula (I), wherein R1, R2, R3, R4, R5, R6, X, and n are as defined for Formula (I) in the description, processes for the preparation of the compounds and new intermediates employed in the preparation, pharmaceutical compositions containing the compounds, and the use of the compounds in the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction.