56777-15-2Relevant articles and documents
Sequence-Specific Cleavage of DNA by N-Bromoacetyldistamycin. Product and Kinetic Analyses
Baker, Brenda F.,Dervan, Peter B.
, p. 2700 - 2712 (1989)
N-Bromoacetyldistamycin (BD) is a designed molecule with two structural domains with distinct functions: sequence specific binding to double helical DNA and cleavage of the DNA backbone.An electrophilic bromoacetyl group is appended to the amino and of th