Journal of the American Chemical Society p. 2700 - 2712 (1989)
Update date:2022-08-05
Topics: Product Analysis Kinetic Analysis DNA
Baker, Brenda F.
Dervan, Peter B.
N-Bromoacetyldistamycin (BD) is a designed molecule with two structural domains with distinct functions: sequence specific binding to double helical DNA and cleavage of the DNA backbone.An electrophilic bromoacetyl group is appended to the amino and of th
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