5678-46-6

Basic information

• Product Name: 3-Amino-3-(2-hydroxyphenyl)propionic acid
• Synonyms: 3-Amino-3-(2-hydroxyphenyl)propanoic acid;3-Amino-3-(2-hydroxyphenyl)propionic acid;3-azanyl-3-(2-hydroxyphenyl)propanoic acid;(RS)-3-Amino-3-(2-hydroxyphenyl)-propionic acid
• CAS NO: 5678-46-6
• Molecular Formula: C₉H₁₁NO₃
• Molecular Weight: 181.19
• Product Categories: B-Amino
• Mol File: 5678-46-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 372.4 °C at 760 mmHg
• Flash Point: 179 °C
• Appearance: /
• Density: 1.329 g/cm³
• Vapor Pressure: 3.33E-06mmHg at 25°C
• Refractive Index: 1.612
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-Amino-3-(2-hydroxyphenyl)propionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Amino-3-(2-hydroxyphenyl)propionic acid(5678-46-6)
• EPA Substance Registry System: 3-Amino-3-(2-hydroxyphenyl)propionic acid(5678-46-6)

Safety Data

• Hazardous Substances Data: 5678-46-6(Hazardous Substances Data)

Usage

General Description

3-Amino-3-(2-hydroxyphenyl)propionic acid is a chemical compound with the molecular formula C9H11NO3. It is also known as meta-tyrosine, and it is an important building block for the synthesis of neurotransmitters and hormones in the body. Meta-tyrosine is a non-proteinogenic amino acid, meaning it is not incorporated into proteins during translation. It is found naturally in certain foods, such as soybeans and spinach, and it can also be synthesized in the laboratory for use in research and pharmaceutical applications. Meta-tyrosine is of interest to scientists for its potential role in the treatment of certain diseases, such as phenylketonuria, where it may help to reduce the levels of harmful metabolites in the body.

InChI:InChI=1/C9H11NO3/c10-7(5-9(12)13)6-3-1-2-4-8(6)11/h1-4,7,11H,5,10H2,(H,12,13)

Upstream product

• 64-17-5 ethanol 
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• 7803-49-8 hydroxylamine 
• 67-56-1 methanol 
• 3943-94-0 (E)-ethyl 2-hydroxycinnamate 
• 91-64-5 coumarin 
• 141-82-2 malonic acid 
• 90-02-8 salicylaldehyde 
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Relevant articles and documents

Synthesis, hypoglycemic effect, antimicrobial and molecular docking studies of organotin(IV) complexes derived from N -phthalimido β-amino acid derivatives

N-Phthalimido β-amino acid derivatives, 3-phthalimido-3(2-hydroxyphenyl) propanoic acid (P2HPA) and 3-phthalimido-3(2-nitrophenyl) propanoic acid (P2NPA) with new series of diand triorganotin(IV) complexes (1-12) have been designed and synthesized. All the ligands and organotin(IV) complexes were characterized by elemental analysis, Fourier transform infrared spectroscopy (FTIR), nuclear magnetic resonance (1H, 13C, 119Sn) spectroscopy and electron ionization mass spectrometry (EI-MS). Synthesized ligands and complexes were screened to determine the antibacterial activity and results showed that the triorganotin(IV) complexes have better activity compared to diorganotin(IV) complexes and ligands. In addition, molecular docking analysis of ligands on the catalytic pocket of sortase A (PDB ID 1T2W) showed that the ligands can bind the active amino acid residues in the pocket. The antioxidant activity was also performed by the DPPH (1,1-diphenyl-2-picrylhydrazyl radical) method and complexes showed better results than ligands. The compounds were also tested in vivo to determine the hypoglycemic activities on different groups of alloxan induced diabetic rabbits. The complexes (1-6) were found better hypoglycemic agents as they stabilized the glucose level to about 175-105 mg dL-1 as compared to ligand P2HPA.