56800-29-4

Upstream product

• 1498-96-0 4-butoxybenzoic acid 
• 123-08-0 4-hydroxy-benzaldehyde 
• 33863-86-4 4-(n-butyloxy)benzoyl chloride 
• 99-96-7 4-hydroxy-benzoic acid 
• 5365-43-5 ethyl 4-butoxybenzoate 
• 120-47-8 Ethyl 4-hydroxybenzoate 
• 5736-88-9 p-butoxybenzaldehyde 

Downstream Products

• 79612-56-9 4-Butoxy-benzoic acid 4-[(E)-octyliminomethyl]-phenyl ester 
• 79612-54-7 4-Butoxy-benzoic acid 4-[(E)-hexyliminomethyl]-phenyl ester 
• 79612-55-8 4-Butoxy-benzoic acid 4-[(E)-heptyliminomethyl]-phenyl ester 
• 78016-56-5 4-Butoxy-benzoic acid 4-((Z)-2-cyano-2-ethoxycarbonyl-vinyl)-phenyl ester 
• 104333-26-8 4-Butoxy-benzoic acid (2R,4aR,8aS)-4-(hexahydro-benzo[1,3]dioxin-2-yl)-phenyl ester 
• 115786-30-6 4-Butoxy-benzoic acid 4-(5-cyano-5-hexyl-[1,3]dioxan-2-yl)-phenyl ester 
• 131340-22-2 4-Butoxy-benzoic acid 4-{5-cyano-5-[2-(4-propyl-cyclohexyl)-ethyl]-[1,3]dioxan-2-yl}-phenyl ester 
• 131340-15-3 4-Butoxy-benzoic acid 4-{5-cyano-5-[2-(4-hexyl-phenyl)-ethyl]-[1,3]dioxan-2-yl}-phenyl ester 
• 115883-81-3 4-Butoxy-benzoic acid 4-((2R,4aR,6S,8aS)-6-pentyl-hexahydro-benzo[1,3]dioxin-2-yl)-phenyl ester 
• 93959-25-2 4-Butoxy-benzoic acid 4-[3-octyl-4-oxo-2-thioxo-thiazolidin-(5Z)-ylidenemethyl]-phenyl ester 
• 79612-53-6 4-Butoxy-benzoic acid 4-[(E)-pentyliminomethyl]-phenyl ester 
• 93959-24-1 4-Butoxy-benzoic acid 4-[3-butyl-4-oxo-2-thioxo-thiazolidin-(5Z)-ylidenemethyl]-phenyl ester 

Relevant academic research and scientific papers

Intercalated liquid-crystalline phases formed by symmetric dimers with an α,ω-diiminoalkylene spacer

Four series of symmetric, dimeric molecules with flexible α,ω-diiminoalkylene spacers have been synthesised and characterised by polarising optical microscopy, differential scanning calorimetry, and X-ray diffraction. The effects on the mesomorphism of th

2-Aryl benzazole derived new class of anti-tubercular compounds: Endowed to eradicate mycobacterium tuberculosis in replicating and non-replicating forms

The high mortality rate and the increasing prevalence of Mtb resistance are the major concerns for the Tuberculosis (TB) treatment in this century. To counteract the prevalence of Mtb resistance, we have synthesized 2-aryl benzazole based dual targeted molecules. Compound 9m and 9n were found to be equally active against replicating and non-replicating form of Mtb (MIC(MABA) 1.98 and 1.66 μg/ml; MIC(LORA) 2.06 and 1.59 μg/ml respectively). They arrested the cell division (replicating Mtb) by inhibiting the GTPase activity of FtsZ with IC50 values 45 and 64 μM respectively. They were also capable of kill Mtb in non-replicating form by inhibiting the biosynthesis of menaquinone which was substantiated by the MenG inhibition (IC50 = 11.62 and 7.49 μM respectively) followed by the Vit-K2 rescue study and ATP production assay.

Liquid crystalline behavior of binary mixtures of structurally dissimilar mesogens and nonmesogens

We have studied eight binary systems comprising three enantiotropic nematogens, namely 4-(4′-n-butyloxybenzoyloxy)phenylazo-4″- fluorobenzene, 4-(4′-n-butyloxybenzo yloxy)benzylidene-4″-fluoro aniline, and 4-(4′-n-heptyloxybenzoyloxy)phenylazo-4″-fl uorobenzene; a monotropic nematogen, viz. 4-(4′-n-dodecyloxybenzoyloxy) napthylazo-4″-fluorobenzene; and three nonmesogens, viz. 4-(4′-n-butyloxy benzoyloxy)benzalde hyde, 4-methoxybenzylidene-4′- chloroaniline, and 4-methoxybenzylidene-4′-toluidine. The central linkage, terminal group, and central ring system of the components have been varied systematically and the effect of these variations has been evaluated on the liquid crystalline properties of the binary mixtures. The mixed mesomorphic properties of these systems are discussed on the basis of their phase diagrams.

Synthesis and mesomorphic investigations of liquid crystalline compounds having a benzothiazole ring

Two homologous series of calamitic liquid crystals containing a benzothiazole ring and two different linkages have been prepared, and their liquid crystalline properties are studied and compared with each other and those of similar structure. The mesogens with only the cinnamate linking group showed better thermal properties than those with an ester. Nematic and smectic phases were observed. All the compounds of both the series were characterized by elemental analysis, FT-IR, mass spectrometry, 1H-NMR, and 13C-NMR. Phase transition temperatures and the thermal parameters were obtained from differential scanning calorimetery (DSC). The textural observations were performed using hot-stage Polarizing Optical Microscopy (POM).

Synthesis, characterization and mesomorphic properties of new rod-like thiophene based liquid crystals

Two new mesogenic homologous series of Schiff base esters, 2-[4-(4-n-Alkoxy benzoyloxy) benzylidenamino] 3-cyno thiophine (Series-A) and Schiff base cinnamates, 2-[4-(4-n-alkoxy cinnamoyloxy) benzylidenamino] 3-cyano thiophene (Series-B), comprising a thiophene moiety were synthesized. Structural elucidation was carried out using elemental analysis and spectroscopic techniques such as FT-IR, 1H-NMR and 13C-NMR, and mass spectrometry. The mesomorphic properties and thermal stabilities of the title compounds were studied by using differential scanning calorimetry and optical polarizing microscopy. All the derivatives are mesomorphic in nature showing the nematic phase, and the higher members of Series-A show a smectic C phase whereas Series-B exhibits only the nematic mesophase. The mesomorphic properties of the present series are compared with other structurally related compounds. Taylor and Francis Group, LLC.

A new way to access chiral liquid crystals: Organocatalyst-mediated synthesis of chiral rod-like liquid crystals

In this article, an asymmetric organocatalytic way to prepare chiral liquid crystals from non-chiral starting materials was described. By using L-proline as the organocatalyst, several new chiral rod-like liquid crystals that are elusive with traditional methods were prepared. In addition, a series of novel enone-containing rod-like liquid crystals were also obtained as side-products. Mesomorphic properties of all new compounds were studied by Polarized Optical Microscope and Differential Scanning Calorimetry. Copyright Taylor & Francis Group, LLC.

Synthesis and characterization of liquid crystalline materials incorporating the novel 4-amino-1,2,4-triazole and isonicotinic acid hydrazide moiety

We report the synthesis and evaluation of thermal behavior of two new mesogenic homologous series of liquid crystalline compound containg 1,2,4-triazole and isonicotinic acid ring at the terminus of the molecule viz. 4-[(4H-1,2,4-triazol-4-ylimino) methyl] phenyl 4-alkoxybenzoate and 4-(2-isonicotinoylcarbonohydrazonoyl) phenyl 4-alkoxybenzoate. Both series have been characterized by elemental analysis, FT-IR, mass spectrometry, 1H-NMR, and 13C-NMR. Phase transition temperatures and the thermal parameters were obtained from differential scanning calorimetry (DSC). The texture observation was performed under polarizing optical microscopy (PMO) attached with Mettler hot stage. All the derivatives are mesomorphic in nature showing nematic phase and the higher member of both series shows smectic phase. The use of isonicotinic acid and triazole as a terminal group has a very dramatic effect on the melting and clearing points. The mesomorphic behavior has been analyzed in terms of structural property relationship.

Synthesis and mesomorphic properties of fluorinated Schiff's base esters containing alkyl and alkoxy end groups

Two series of fluorinated Schiff's base esters have been synthesized and characterized. Their chemical structures were identified by FTIR, 1H NMR, and elemental analysis (EA). Their mesomorphic properties were studied by polarizing optical, microscopy (PO

Synthesis, characterization, and mesomorphic properties of new liquid-crystalline compounds involving ester-azomethine central linkages, lateral substitution, and a thiazole ring

In continuation with our work on liquid crystals with unconventional molecular structures, two homologous series that have 1,4-disubstitution and 1,3,4-trisubstitution in the central phenyl ring, such as 2[(4-n-alkoxy- benzyloxy) phenyl azomethine]-5-methyl thiazole and 2-[(4-n-alkoxy-benzyloxy)-2- hydroxy salicyladimine]-5-methyl thiazole, have been synthesized. They have been characterized by elemental analysis, FT-IR, 1HNMR, 13CNMR, and mass spectrometry. The liquid-crystalline behavior of these compounds was observed by differential scanning calorimetry (DSC) and polarizing microscopy. All the compounds of the 1,4-disubstituted series show an enantiotropic nematic phase only, whereas the compounds of the 1,3,4-trisubstituted series show smectic and nematic phases. Some mesogens with a lateral hydroxy group were also synthesized to evaluate the effect of this group on melting point, transition temperatures, and mesophase morphology.

Synthesis and mesomorphic characterisation of chiral homologues

Chiral liquid crystals have attracted considerable interest as they exhibit a good variety of modulated phases. We have synthesised a homologous series viz., 4-(4!-n-alkoxy benzoyloxy) benzylidene-4!!-1-(s)-methyl propoxy anilines, incorporating a terminal chiral centre, inorder to obtain better understanding of the relationship between molecular structure and appearance of SmC*phase in the molecules. It is observed that, in the present series the lower members upto butyl are pure nematogens, while pentyl to hexadecyl derivatives exhibit classical smectic as well as nematic mesophases. An additional smectic C* phase is observed in the middle octyl to dodecyl homologues. The homologues have been characterised by IR, NMR and DSC. Their mesomorphic properties have been compared with structurally related homologous series.