56813-85-5Relevant academic research and scientific papers
FeX3-promoted intermolecular addition of benzylic alcohols to aromatic alkynes: A mild and efficient strategy for the synthesis of alkenyl halides
Ren, Kai,Wang, Min,Wang, Lei
experimental part, p. 565 - 571 (2010/04/28)
A convenient, effective, mild and simple strategy has been developed for the synthesis of alkenyl halides by the intermolecular addition of benzylic alcohols to aromatic alkynes. The reactions were carried out in the presence of iron(III) bromide or chloride in 1, 2-dibromoethane without additives in air at room temperature. Alkenyl bromides and chlorides were obtained with high regio- and stereoselectivity (E/Z up to 99:1) in good-to-excellent yields in 0.5-1 h under mild reaction conditions.
A mild and efficient iron-catalyzed synthesis of alkenyl halides via direct addition of benzyl halides to arylalkynes
Liu, Zhongquan,Wang, Jianguo,Zhao, Yankai,Zhou, Bo
supporting information; scheme or table, p. 371 - 374 (2009/10/20)
An efficient and mild iron-catalyzed synthesis of alkenyl halides has been developed via direct carbon-carbon bond formation by using benzyl halides and arylalkynes.
