5682-80-4

Upstream product

• 141-79-7 4-methyl-pent-3-en-2-one 
• 101458-38-2 2-methyl-1,2-dibromopropyl methyl ketone 
• 67-56-1 methanol 
• 5239-69-0 2,2-dibromo-3,3-dimethyl-1-methylenecyclopropane 
• 83769-12-4 (2-Bromo-1,1-dimethyl-3-oxo-butyl)-dimethyl-sulfonium; bromide 
• 7664-93-9 sulfuric acid 
• 58898-22-9 1,1-dibromo-2,2,3-trimethyl-3-trimethylsilanyloxy-cyclopropane 

Downstream Products

• 1578-14-9 2-bromo-3-methyl-crotonic acid 
• 41436-49-1 4-Acetyl-4-brom-5,5-dimethylcyclohexen 
• 7493-58-5 4-methyl-2,3-pentanedione 
• 66613-07-8 4-methyl-3-phenylthio-3-penten-2-one 
• 882-33-7 diphenyldisulfane 

Relevant academic research and scientific papers

Novel diastereoselective allene formation by an ene reaction of significantly twisted 1,3-dienes with singlet oxygen

The highly diastereoselective allene formation by photosensitized oxygenation of the significantly twisted novel 1,3-dienes which possess an sp3 chiral center due to a secondary hydroxy group and a tertiary alkoxy group at allylic positions is described.

A convenient halogenation of α,β-unsaturated carbonyl compounds with OXONE and hydrohalic acid (HBr,HCl)

Mixtures of OXONE and hydrobromic acid or hydrochloric acid afford solutions of bromine or chlorine, respectively, α-Bromo- or α-chloro-α,β-unsaturated carbonyl compounds were prepared by addition of hydrobromic acid or hydrochloric acid to the mixture of

Oxidation of α,β-enones and alkenes with oxone and sodium halides: A convenient laboratory preparation of chlorine and bromine

Mixtures of oxone and sodium chloride or sodium bromide afford solutions of chlorine or bromine, respectively. These solutions effectively add chlorine and bromine to α,β-enones and alkenes. The method affords improved yields of 3-alkyl-2-halo-2-cycloalkenones which are sometimes difficult to prepare.

REACTION OF METHYLENE-gem-DIBROMOCYCLOPROPANES WITH METHANOL IN THE PRESENCE OF SILVER TRIFLUOROACETATE

The methanolysis of methylene-gem-dibromocyclopropanes in the presence of silver trifluoroacetate leads to the products from opening of the three-membered ring.Their ratio is determined by the charge distribution in the intermediate allenyl cation and by the relative stability of the reaction products.

NOVEL BROMINATION REAGENTS. HEXABROMOCYCLOPENTADIENE: BROMINATION OF ACTIVATED SATURATED SITES

Hexabromocyclopentadiene (HBC) readily brominates α-keto and benzylic sites, apparently by bromonium ion transfer.

The electrophilic addition of dimethylbromosulfonium bromide to conjugated enones: efficient synthesis of α-bromo enones

Dimethylbromosulfonium bromide reacted readily with many enones at 0 deg C or lower to precipitate α-bromo-β-sulfonium conjugated enones.These salts eliminate a proton and dimethylsulfide readily with aqueous potassium carbonate to give excellent yields o

α-Keto Dianion Precursors via Conjugate Additions to Cyclic α-Bromo Enones

Successful conjugate to 2-bromocyclohexenone and 2-bromocyclopentenone have been achieved with a variety of lithium homocuprates, mixed cyanocuprates, and lithium tri-sec-butylborohydride as well.In all cases the resulting α-bromo enolate anions could be