5684-70-8

Usage

InChI:InChI=1/C14H26O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14(15)16/h9-10H,2-8,11-13H2,1H3,(H,15,16)/b10-9-

Upstream product

• 124-19-6 nonan-1-al 
• 42186-61-8 5-(Triphenyl-λ⁵-phosphanylidene)-pentanoic acid anion 
• 74088-20-3 1-bromo-(Z)-4-tridecene 
• 17814-85-6 (4-carboxybutyl)triphenylphosphonium bromide 
• 2067-33-6 5-bromopentanoic acid 
• 94519-25-2 Methanesulfonic acid (Z)-tridec-4-enyl ester 
• 75568-01-3 4(Z)-tridecene-1-ol 
• 127089-53-6 1-cyano-(Z)-4-tridecene 

Downstream Products

• 15266-35-0 dihydroevocarpine 
• 35153-13-0 Z-5-tetradecen-1-yl acetate 
• 40642-42-0 (Z)-tetradec-5-en-1-ol 
• 28369-26-8 Methyl (Z)-tetradec-5-enoate 

Relevant academic research and scientific papers

Formation of COOH-Ylides, and Their Reactivities and Selectivities in Wittig Reactions

Whereas two equivalents of base are typically required to prepare carboxylate (CO 2-) ylides [Ph 3 P + C - (H)-alk-CO 2- ] (alk = alkanediyl) from carboxy (CO 2 H) pho

Design, synthesis and antimycobacterial activities of 1-methyl-2-alkenyl- 4(1H)-quinolones

A series of 23 new 1-methyl-2-alkenyl-4(1H)quinolones have been synthesized and evaluated in vitro for their antimycobacterial activities against fast growing species of mycobacteria, such as Mycobacterium fortuitum, M. smegmatis and M. phlei. The compounds displayed good to excellent inhibition of the growth of the mycobacterial test strains with improved antimycobacterial activity compared to the hit compound, evocarpine. The most active compounds, which possessed chain length of 11-13 carbons at position-2 displayed potent inhibitory effects with an MIC value of 1.0 mg/L. In a human diploid embryonic lung cell line, MRC-5 cytotoxicity assay, the alkaloids showed weak to moderate cytotoxic activity. Biological evaluation of these evocarpine analogues on the less pathogenic fast growing strains of mycobacteria showed an interesting antimycobacterial profile and provided significant insight into the structure-activity relationships.

Synthesis of (Z)-5-dodecenyl and (Z)-5-tetradecenyl acetates: Pheromone components of Lepidoptera noctuidae species

(Z)-5-Dodecenyl acetate (1) and (Z)-5-tetradecenyl acetate (2), the pheromone components of Lepidoptera noctuidae species have been synthesised by a new approach from the corresponding (Z)-4-undecenol (3) and (Z)-4-tridecenol (4), both of which have been obtained from a common intermediate, viz. the dianion of 4-pentyn-1-ol.

TRANS STEREOSELECTIVITY IN THE REACTION OF (4-CARBOXYBUTYLIDENE)TRIPHENYLPHOSPHORANE WITH AROMATIC ALDEHYDES

Aromatic aldehydes react with 1 to give predominantly trans 6-aryl-5-hexenoic acids, under special conditions.A systematic study of the reaction of 1 with aldehydes, in a preliminary attempt to define the cause and scope of the trans stereoselectivity, is reported.