5685-05-2

Basic information

• Product Name: 2-Mercaptothiazole
• Synonyms: 2-Mercapto-1,3-thiazole;2-Thiazolethiol;4-Thiazoline-2-thione;Thiazoline-2-thione;2-Mercaptothiazole;Thiazole-2(3H)-thione;2(3H)-Thiazolethione (9ci);4-Thiazoline-2-thione (8ci)
• CAS NO: 5685-05-2
• Molecular Formula: C₃H₃NS₂
• Molecular Weight: 117.19
• EINECS: 423-680-4
• Product Categories: API intermediates
• Mol File: 5685-05-2.mol
• Article Data: 9

Chemical Properties

• Melting Point: 80 °C(Solv: water (7732-18-5))
• Boiling Point: 194.7 °C at 760 mmHg
• Flash Point: 71.5 °C
• Appearance: /
• Density: 1.47 g/cm³
• Vapor Pressure: 0.437mmHg at 25°C
• Refractive Index: 1.754
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 8.58±0.20(Predicted)
• CAS DataBase Reference: 2-Mercaptothiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Mercaptothiazole(5685-05-2)
• EPA Substance Registry System: 2-Mercaptothiazole(5685-05-2)

Safety Data

• Statements: R20/22:
• Safety Statements: S22;S36/37:
• Hazardous Substances Data: 5685-05-2(Hazardous Substances Data)

Usage

General Description

2-Mercaptothiazole is a chemical compound with a molecular formula of C3H3NS2. It is a thiazole derivative with a mercapto functional group, and is used in various industrial applications. 2-Mercaptothiazole is known for its strong odor, and is used as an intermediate in the synthesis of pharmaceuticals, pesticides, and other organic compounds. It is also used as a corrosion inhibitor in the petroleum industry, due to its ability to inhibit the corrosion of metals. Additionally, 2-Mercaptothiazole has been studied for its potential anti-fungal and anti-bacterial properties, making it a promising candidate for pharmaceutical research.

InChI:InChI=1/C3H3NS2/c5-3-4-1-2-6-3/h1-2H,(H,4,5)

Upstream product

• 3034-53-5 2-bromo-1,3-thiazole 
• 107-20-0 2-chloroethanal 
• 513-74-6 ammonium dithiocarbamate 
• 64-17-5 ethanol 
• 17157-48-1 bromoacetaldehyde 

Downstream Products

• 143122-27-4 (4S,5S)-3-(tert-butoxycarbonyl)-4-(cyclohexylmethyl)-2,2-dimethyl-5-<2-(2-thiazolylthio)ethyl>oxazolidine 
• 119982-81-9 1-[4-Nitro-3-(thiazol-2-ylsulfanyl)-phenyl]-ethanone 
• 179687-74-2 2-(2-chloro-4-nitrophenylsulfanyl)thiazole 
• 161385-94-0 4'-(2-thiazolylthio)acetophenone 
• 263171-66-0 3-chloro-4-(1,3-thiazol-2-ylsulfanyl)aniline 
• 1185189-20-1 4-(3,5-dimethylphenoxy)-3-iodo-6-methyl-5-(thiazol-2-ylthiomethyl)pyridin-2(1H)-one 
• 156-57-0 2-mercaptoethylamine hydrochloride 
• 1204227-20-2 4-(4',5'-dihydrothiazol-2'-ylthio)benzene-1,2-diol 
• 1204227-21-3 4-(4',5'-dihydrothiazol-2'-ylthio)-5-methylbenzene-1,2-diol 
• 1521221-87-3 4-(4',5'-dihydrothiazol-2'-ylthio)-5-ethylbenzene-1,2-diol 
• 1560769-18-7 C₂₄H₁₇NS 
• 1598407-60-3 3-mesityl-2-oxo-6-(2-(thiazol-2-ylthio)ethyl)-2H-pyran-4-yl pivalate 

Relevant articles and documents

Discovery of a series of 5-phenyl-2-furan derivatives containing 1,3-thiazole moiety as potent Escherichia coli β-glucuronidase inhibitors

Gut microbial β-glucuronidases have drawn much attention due to their role as a potential therapeutic target to alleviate some drugs or their metabolites-induced gastrointestinal toxicity. In this study, fifteen 5-phenyl-2-furan derivatives containing 1,3

Novel S-Thiazol-2-yl-furan-2-carbothioate Derivatives as Potential T3SS Inhibitors against Xanthomonas oryzae on Rice

Bacterial leaf blight (BLB) caused by Xanthomonas oryzae pv oryzae (Xoo) is considered as the most destructive disease of rice. The use of bactericides is among the most widely used traditional methods to control this destructive disease. The excessive an

Compounds containing a N-heteroaryl moiety linked to fused ring moieties for the inhibition of NAD(P)H oxidases and platelet activation

The invention relates to compounds containing a N-heteroaryl moiety, which is linked via oxygen, sulfur or nitrogen, or via a methylene bridge and oxygen, sulfur or nitrogen to a fused ring moiety, in particular to the 1,2,3-triazolo[4,5-d]pyrimidine-7-yl radical. The invention also relates to a process for the preparation of said compounds and the use thereof in drugs for the treatment of NAD(P)H oxidases-related diseases and disorders and inhibition of platelet activation.