568583-35-7Relevant academic research and scientific papers
7-Oxo-4,7-dihydrothieno[3,2-b]pyridine-6-carboxamides: Synthesis and biological activity of a new class of highly potent inhibitors of human cytomegalovirus DNA polymerase
Larsen, Scott D.,Zhang, Zhijun,DiPaolo, Brian A.,Manninen, Peter R.,Rohrer, Douglas C.,Hageman, Michael J.,Hopkins, Todd A.,Knechtel, Mary L.,Oien, Nancee L.,Rush, Bob D.,Schwende, Francis J.,Stefanski, Kevin J.,Wieber, Janet L.,Wilkinson, Karen F.,Zamora, Kathyrn M.,Wathen, Michael W.,Brideau, Roger J.
, p. 3840 - 3844 (2007)
We report a new class of non-nucleoside antivirals, the 7-oxo-4,7-dihydrothieno[3,2-b]pyridine-6-carboxamides, some of which possess remarkable potency versus a broad spectrum of herpesvirus DNA polymerases and excellent selectivity compared to human DNA
Antiviral agents
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Page 18, (2010/02/07)
The invention provides a compound of formula I: wherein G, R2, and R3 have any of the values defined in the specification, or a pharmaceutically acceptable salt thereof, as well as processes and intermediates useful for preparing such compounds or salts, and methods of treating a herpesvirus infection using such compounds or salts.
