568587-95-1

Upstream product

• 115962-35-1 (3S)-2-tert-butoxycarbonyl-1,2,3,4-tetrahydroisoquinole-3-carboxylic acid 
• 183958-71-6 tert-butyl (3S)-3-(hydroxymethyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate 
• 150417-17-7 (3S)-3-Aminomethyl-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester 
• 568587-85-9 3-[(3-phenyl-ureido)-methyl]-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester 
• 568587-87-1 1-Phenyl-3-[(S)-1-(1,2,3,4-tetrahydro-isoquinolin-3-yl)methyl]-urea 
• 357339-32-3 Boc-L-Tic-CH₂N₃ 
• 568587-94-0 2-[({3-[(3-phenyl-ureido)-methyl]-3,4-dihydro-1H-isoquinoline-2-carbothioyl}-amino)-methyl]-pyrrolidine-1-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

New scaffolds in the development of Mu opioid-receptor ligands

A new class of μ selective receptor antagonists has been developed using a combinatorial approach based on previously reported Dmt-Tic dipeptide ligands. Modified tetrahydroisoquinoline (Tiq) residues were reacted with different electrophiles in order to