5686-93-1

Usage

Uses

Used in Pharmaceutical Industry:
3-Indazolinone is used as a key building block for the synthesis of various biologically active compounds, contributing to the development of innovative drugs.
Used in Oncology:
In the field of oncology, 3-Indazolinone is utilized for its potential in the development of new anticancer drugs, targeting a range of malignancies.
Used in Central Nervous System Disorders:
3-Indazolinone is employed in the research and development of medications aimed at treating central nervous system disorders, leveraging its structural and functional attributes.
Used in Antimicrobial Development:
3-Indazolinone is used as a starting point in the creation of new antibiotics, given its antimicrobial properties, which can be harnessed to combat resistant bacterial strains.
Used in Antiviral Drug Development:
In antiviral research, 3-Indazolinone is explored for its potential to form the basis of new antiviral medications, capitalizing on its antiviral properties to address viral infections and diseases.

Upstream product

• 7364-25-2 3-indazolinone 

Relevant academic research and scientific papers

Electrosynthesis of cyclic α-carbonylazo compounds. Chemical stability of the electrogenerated dienophiles and in situ trapping of dienes

Dienophilic cyclic α-carbonylazo compounds were prepared electrochemically by oxidation of the corresponding hydrazino compounds using a flow cell fitted with a graphite felt anode in acidic methanol or acetonitrile. The instability of these compounds in methanol was first studied. In situ Diels-Alder additions of these electrogenerated dienophiles and various dienes were performed in relatively good yields in acidic methanol or acetonitrile.

Therapeutic preparations containing indazole derivatives

The invention concerns pharmaceutical compositions containing a 1,2-dihydro-3H-indazol-3-one derivative of the formula I STR1 wherein Ra is hydrogen, halogeno, nitro, hydroxy, (2-6C)alkanoyloxy, (1-6C)alkyl, (1-6C)alkoxy, fluoro-(1-4C)alkyl, (2-6C)alkanoy

Heterocyclic agents

The invention concerns a 1,2-dihydro-3H-indazol-3-one derivative of formula I STR1 wherein Ra is hydrogen, halogeno, hydroxy, cyano, trifluoromethyl, 1-6C)alkyl or (1-6C)alkoxy; Rb is hydrogen or (1-6C)alkyl; Rc is hydrogen, (1-8C)alkyl or (3-8C)alkenyl;

Preparation of hexahydroindazolones

This invention relates to a novel process for the preparation of hexahydroindazolones useful as herbicides by condensation of an aromatic hydrazine source with a cyclohexanone 2-carboxamide, under controlled reaction conditions.