5691-54-3

Basic information

• Product Name: 2,5-Dimethoxy-3,6-dimethyl-2,5-cyclohexadiene-1,4-dione
• Synonyms: 2,5-Dimethoxy-3,6-dimethyl-1,4-benzoquinone;2,5-Dimethoxy-3,6-dimethyl-2,5-cyclohexadiene-1,4-dione;2,5-Dimethoxy-3,6-dimethyl-p-benzoquinone
• CAS NO: 5691-54-3
• Molecular Formula: C₁₀H₁₂O₄
• Molecular Weight: 0
• Mol File: 5691-54-3.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,5-Dimethoxy-3,6-dimethyl-2,5-cyclohexadiene-1,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Dimethoxy-3,6-dimethyl-2,5-cyclohexadiene-1,4-dione(5691-54-3)
• EPA Substance Registry System: 2,5-Dimethoxy-3,6-dimethyl-2,5-cyclohexadiene-1,4-dione(5691-54-3)

Safety Data

• Hazardous Substances Data: 5691-54-3(Hazardous Substances Data)

Upstream product

• 18735-47-2 MEDZQ 
• 3117-03-1 2,5-dimethoxyquinone 
• 67-68-5 dimethyl sulfoxide 
• 186581-53-3 diazomethane 
• 25653-42-3 2-hydroxy-5-methoxy-p-xyloquinone 
• 2654-72-0 2,5-dihydroxy-3,6-dimethyl-1,4-benzoquinone 
• 173348-65-7 2,5-diacetoxy-p-xyloquinone 
• 173348-62-4 2-acetoxy-5-hydroxy-p-xyloquinone 
• 213831-85-7 2-acetoxy-5-methoxy-p-xyloquinone 

Relevant articles and documents

Preparation and structure-activity relationships of novel asterriquinone derivatives

Asterriquinone (ARQ, la) is an antitumor metabolite of Aspergillus terreus IFO 6123. To gain insight into the structure-activity relationships of ARQ, a series of chemically modified derivatives (1 - 6), the ARQ analogues (b - e) and the 2,5-dihydroxy-p-benzoquinone analogues (f - h), were prepared, and cytotoxic activity against mouse leukemia P388 cells investigated. Results indicated that: 1) at least one hydroxy group or acetoxy group in the p-benzoquinone moiety is important to exhibit cytotoxicity; 2) in the p-benzoquinone moiety, a single methoxy group and/or one acetoxy group substitution showed more potent cytotoxicity than when two hydroxy groups are substituted (1); 3) the indole ring is important for the cytotoxicity of ARQ analogues; 4) the 1,1-dimethyl-2-propenyl group in the indole ring is not important for the cytotoxic activity of ARQ.

Dimethyl sulfoxide and anhydrous copper (II) sulfate as alkylating reagent for 1,4-quinones

1,4-Quinones and its derivatives have been alkylated by dimethyl sulfoxide in the presence of anhydrous copper (II) sulfate at the active quinonoid position selectively, in a facile single step reaction with good yields.

Triphendioxazine dyestuffs

Triphendioxazine dyestuffs of the formula STR1 having the substituent meanings specified in the descriptive part, are highly suitable for dyeing and printing hydroxyl- or amido-containing materials, in particular fibre materials, and produce wash-fast dyeings and prints.