5692-35-3

Usage

Uses

Used in Pharmaceutical Industry:
Benzamide, 3,5-dimethyl(7CI,8CI,9CI) is utilized as a building block for the synthesis of pharmaceutical compounds. Its structural properties allow for the creation of new molecules with potential therapeutic applications, contributing to the development of novel drugs.
Used in Chemical Industry:
In the chemical industry, Benzamide, 3,5-dimethyl(7CI,8CI,9CI) serves as a versatile intermediate in the synthesis of various organic compounds. Its presence in chemical reactions can lead to the formation of a range of products used in different sectors.
Used in Organic Synthesis:
Benzamide, 3,5-dimethyl(7CI,8CI,9CI) is employed as a reagent in organic synthesis, facilitating the creation of complex organic molecules. Its participation in these reactions is crucial for achieving specific synthetic goals.
Used in Research:
As a research intermediate, Benzamide, 3,5-dimethyl(7CI,8CI,9CI) is instrumental in scientific investigations. It aids researchers in understanding the properties and behaviors of related compounds, thus advancing knowledge in organic chemistry and related fields.

InChI:InChI=1/C9H11NO/c1-6-3-7(2)5-8(4-6)9(10)11/h3-5H,1-2H3,(H2,10,11)

Upstream product

• 6613-44-1 3,5-dimethylbenzoyl chloride 
• 64-17-5 ethanol 
• 79988-86-6 N-<(α-acetoxy)-4-pyridylmethyl>-3,5-dimethylbenzamide 
• 108-24-7 acetic anhydride 
• 72569-75-6 N-(2-pyridylmethyl)-3,5-dimethylbenzamide N-Oxide 
• 79988-88-8 N-<(α-hydroxy)-4-pyridylmethyl>-3,5-dimethylbenzamide 
• 108462-88-0 (E)-ethyl 2-cyano-3-(4-pyridyl)-3-(3,5-dimethylbenzoylamino)acrylate 
• 72583-99-4 4-(3,5-Dimethylbenzoylaminomethyl)pyridine 1-Oxide 
• 108-67-8 1,3,5-trimethyl-benzene 
• 5779-95-3 3,5-dimethylbenzaldehyde 
• 556-96-7 5-bromo-1,3-xylene 
• 22445-42-7 3,5-dimethylbenzonitrile 
• 201230-82-2 carbon monoxide 
• 22445-41-6 3,5-dimethylphenyl iodide 

Downstream Products

• 22445-42-7 3,5-dimethylbenzonitrile 
• 108-69-0 3,5-dimethylaminoaniline 
• 499-06-9 3,5-dimethylbenzoic acid 
• 156092-23-8 (-)-(4S)-4,5-Dihydro-2-(3',5'-dimethylphenyl)-4-isopropyloxazole 
• 78710-55-1 3,5-dimethylbenzyl amine 
• 54564-93-1 N-3,5-Dimethylbenzoyl-N'-methylsulfonyltrichlormethansulfinamidin 
• 54564-79-3 N-3.5-Dimethylbenzoyl-N'-phenylsulfonyltrichlormethansulfinamidin 
• 54564-81-7 N-3.5-Dimethylbenzoyl-N'-p-tolylsulfonyltrichlormethansulfinamidin 
• 54564-80-6 N-3.5-Dimethylbenzoyl-N'-p-chlorphenylsulfonyltrichlormethansulfinamidin 
• 899426-93-8 C₁₇H₁₈⁽²⁾H₃NO 
• 252286-43-4 {4-[(3,5-dimethyl-benzylamino)-methyl]-phenyl}-methanol 
• 188984-18-1 3-chloromethyl-5-methyl-benzonitrile 
• 2050-45-5 N-acetyl-3,5-dimethylaniline 
• 124289-23-2 3-(bromomethyl)-5-methylbenzonitrile 

Relevant academic research and scientific papers

Mechanism of Acid-Catalyzed Proton Exchange in Amides

The kinetics of acid-catalyzed proton exchange in a series of primary amides were studied by NMR.The saturation-transfer method measures independently all six rate constants for exchange among sites HE, HZ, and solvent OH (usually et

Method for preparing primary and secondary amide compounds

The invention belongs to the field of organic chemical synthesis, and particularly relates to a method for preparing primary and secondary amide compounds. The method for preparing primary and secondary amide compounds comprises the following steps of carrying out catalytic reduction on an N-substituted amide compound at 30-130 DEG C by using a protic solvent as a reduction reagent and a dichloro(p-methyl isopropylbenzene) ruthenium (II) dimer complex as a catalyst to obtain a reaction solution after the reduction reaction is finished, and carrying out post-treatment on the reaction solution to obtain the corresponding primary amide compound or secondary amide compound. According to the method for preparing the primary and secondary amide compounds, the transfer hydrogenation reaction of nitrogen-oxygen and nitrogen-carbon bonds is realized, the reaction conditions are mild and simple, the substrate application range is wide, the operation is convenient, and the corresponding primary amide compound or secondary amide compound is obtained with high efficiency and high selectivity.

Efficient nitriding reagent and application thereof

The invention discloses an efficient nitriding reagent and application thereof, wherein the nitriding reagent comprises nitrogen oxide, an active agent, a reducing agent and an organic solvent. By applying the nitriding reagent, nitrogen-containing compounds such as amide, nitrile and the like can be produced, and the method is simple in condition, low in waste discharge amount and simple in reaction equipment.

Supported palladium catalyzed aminocarbonylation of aryl iodides employing bench-stable CO and NH3surrogates

A simple, efficient and phosphine free protocol for carbonylative synthesis of primary aromatic amides under polystyrene supported palladium (Pd?PS) nanoparticle (NP) catalyzed conditions has been demonstrated. Herein, instead of using two toxic and difficult to handle gases simultaneously, we have employed the solid, economical, bench stable oxalic acid as the CO source and ammonium carbamate as the NH3source in a single pot reaction. For the first time, we have applied two non-gaseous surrogates simultaneously under heterogeneous catalyst (Pd?PS) conditions for the synthesis of primary amides using an easy to handle double-vial (DV) system. The developed strategy showed a good functional group tolerance towards a wide range of aryl iodides and afforded primary aromatic amides in good yields. The Pd?PS catalyst was easy to separate and can be recycled up to four consecutive runs with small loss in catalytic activity. We have successfully extended the scope of the methodology to the synthesis of isoindole-1,3-diones from 1,2-dihalobenzene, 2-halobenzoates and 2-halobenzoic acid following double and single carbonylative cyclization approaches.

Nitromethane as a nitrogen donor in Schmidt-type formation of amides and nitriles

The Schmidt reaction has been an efficient and widely used synthetic approach to amides and nitriles since its discovery in 1923. However, its application often entails the use of volatile, potentially explosive, and highly toxic azide reagents. Here, we report a sequence whereby triflic anhydride and formic and acetic acids activate the bulk chemical nitromethane to serve as a nitrogen donor in place of azides in Schmidt-like reactions. This protocol further expands the substrate scope to alkynes and simple alkyl benzenes for the preparation of amides and nitriles.

Ti-superoxide catalyzed oxidative amidation of aldehydes with saccharin as nitrogen source: Synthesis of primary amides

A new heterogeneous catalytic system (Ti-superoxide/saccharin/TBHP) has been developed that efficiently catalyzes oxidative amidation of aldehydes to produce various primary amides. The protocol employs saccharin as amine source and was found to tolerate a wide range of substrates with different functional groups. Moderate to excellent yields, catalyst reusability and operational simplicity are the main highlights. A possible mechanism and the role of the catalyst in oxidative amidation have also been discussed.

COMPOSITION AND LIGHT-EMITTING DEVICE USING THE SAME

A composition containing phosphorescent compounds represented by formula (1) and formula (2) are provided. M1 and M2 each represent an iridium atom, n1 and n3 each denote an integer of 1 or more; n and n4

METAL COMPLEX AND LIGHT EMITTING DEVICE USING THE SAME

Provided is a metal complex excellent in light emission stability. The metal complex is represented by the formula (1): wherein M represents an iridium atom or the like, n1 represents an integer of 1 to 3, n2 represents an integer o

LIGHT-EMITTING COMPOUND

A compound of formula (I): wherein M is a transition metal; x is at least 1; z is 0 or a positive integer; L1 is a ligand selected from one of ligands (II-A), (II-B); L2 is a ligand selected from another of ligands of formulae (II-A), (II-B) and (II-C); and L3 is a ligand other than a ligand of formulae (II-A), (II-B) or (II-C): (II-A) (II-B) (II-C) in which each of R1 - R6 is substituent and Ar1 - Ar3 are each an unsubstituted or substituted aryl or heteroaryl group. The compound of formula (I) may be used as a phosphorescent light-emitting material of an organic light-emitting device.

A Brevibacterium process for synthesizing amide

The invention discloses a method for synthesizing amide through nitrile hydrolysis. The method comprises the following steps: adding nitrile, acetaldoxime, water, a water-soluble rhodium complex to a reaction vessel, and cooling to room temperature after reaction of a reaction mixture for several hours at the temperature of 50-80 DEG C; and adding ethyl acetate for extraction so as to obtain an organic layer, and carrying out rotary evaporation to remove a solvent, thus obtaining a target product. Compared with a method for synthesizing amide through nitrile hydrolysis by using oxime as a water source in a transition metal catalysis process, the method has the advantages that a used catalyst is low in loading and does not contain a phosphine ligand seriously polluting environments, synthesis can be performed in air, and nitrogen protection is not needed; and therefore, the method meets the green chemistry requirements and has a wide development prospect.