56933-07-4Relevant academic research and scientific papers
Synthesis of the hyper-branched core tetrasaccharide motif of chloroviruses
Mishra, Bijoyananda,Manmode, Sujit,Walke, Gulab,Chakraborty, Saptashwa,Neralkar, Mahesh,Hotha, Srinivas
, p. 1315 - 1328 (2021/02/26)
Chemical synthesis of complex oligosaccharides, especially those possessing hyper-branched structures with one or multiple 1,2-cisglycosidic bonds, is a challenging task. Complementary reactivity of glycosyl donors and acceptors and proper tuning of the s
Delta-oleanolic acid saponin compound and medical application thereof
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Paragraph 0065-0067; 0069, (2020/12/31)
The invention discloses a delta-oleanolic acid saponin compound and medical application thereof. The delta-oleanolic acid saponin compound is a compound with a structural formula shown as a formula (I), and pharmaceutically acceptable salt or ester or pro
Total syntheses of schizandriside, saracoside and (±)-isolariciresinol with antioxidant activities
Sampei, Mana,Arai, Midori A.,Ishibashi, Masami
, p. 651 - 654 (2018/04/16)
Lignans are widely distributed in plants and exhibit significant pharmacological effects, including anti-tumor and antioxidative activities. Here, we describe the total synthesis of schizandriside (1), a compound we previously isolated from Saraca asoca b
Convergent strategy for the synthesis of S-linked oligoxylans
Bonora, Beatrice,Boos, Irene,Clausen, Mads H.
supporting information, p. 53 - 57 (2017/03/31)
Arabinoxylans (AX) are a major class of hemicellulose and an important polysaccharide component of lignocellulosic biomass. To utilize the glycan polymer effectively, it is desirable to learn more about the enzymatic hydrolysis of AXs. Well-defined glycan
THIOPYRANOSE COMPOUND AND METHOD FOR PRODUCING SAME
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Paragraph 0479; 0486; 0487; 0488; 0489, (2016/12/26)
There is provided a production method of a thiopyranose compound represented by the following Formula (2) by reacting a compound represented by the following Formula (1) with a sulfur compound. X represents a leaving group. A represents an oxygen atom or
Tandem Allylboration-Prins Reaction for the Rapid Construction of Substituted Tetrahydropyrans: Application to the Total Synthesis of (-)-Clavosolide A
Millán, Alba,Smith, James R.,Chen, Jack L.-Y.,Aggarwal, Varinder K.
, p. 2498 - 2502 (2016/02/18)
Tetrahydropyrans are common motifs in natural products and have now been constructed with high stereocontrol through a three-component allylboration-Prins reaction sequence. This methodology has been applied to a concise (13 steps) and efficient (14 % ove
Facile synthesis of the pentasaccharide repeating unit of the exopolysaccharide from Cryptococcus neoformans serotype D
Zhuo, Xiao-Bin,Zou, Yan,Huang, Sheng-Jun,Liao, Jun,Hu, Hong-Gang,Zhao, Qing-Jie,Wu, Qiu-Ye
, p. 618 - 626 (2015/06/02)
Abstract β-D-GlcpA-(1→2)-[β-D-Xylp-(1→2)-α-D-Manp-(1→3)]-α-D-Manp-(1→3)-α-D-Manp, the repeating unit of the exopolysaccharide from Cryptococcus neoformans serotype D, was synthesized as its 4-methoxyphenyl glycoside. The approach presented here also provi
Total Synthesis of Linckosides A and B, the Representative Starfish Polyhydroxysteroid Glycosides with Neuritogenic Activities
Zhu, Dapeng,Yu, Biao
supporting information, p. 15098 - 15101 (2015/12/18)
Linckosides A and B, two starfish metabolites with promising neuritogenic activities, are synthesized in a longest linear sequence of 32 steps and 0.5% overall yield; this represents the first synthesis of members of the polyhydroxysteroid glycoside family, which occur widely in starfishes.
Synthesis of a chlorogenin glycoside library using an orthogonal protecting group strategy
Wang, Ying-Hsin,Yeh, Hsien-Wei,Wang, Hsiao-Wen,Yu, Chia-Chun,Guh, Jih-Hwa,Liu, Der-Zen,Liang, Pi-Hui
, p. 118 - 135 (2013/07/27)
Naturally occurring spirostanol saponins bear a chacotriose, α-l-rhamnopyranosyl-(1→2)-[α-l-rhamnopyranosyl-(1→4)] -β-d-glucopyranose residue as the oligosaccharide moiety which is believed to be important for biological activity. Herein the development of a concise, combinatorial method for the synthesis of two series of glycan variants at the 2′ and/or 4′ positions of chacotriose is described and the structure-activity relationships of the glycone part at 3-OH of chlorogenin investigated. These compounds were found to be weakly-cytotoxic toward leukemia cell lines CCRF and HL-20, indicating that the chacotriose moiety is important for anticancer activity.
A new method for selective deprotection of anomeric N,O -dimethylhydroxylamine promoted by TMSCl
Huang, Shengjun,Liao, Jun,Zhao, Qingjie,Chai, Xiaoyun,Wang, Baogang,Yu, Shichong,Wu, Qiuye
, p. 158 - 168 (2013/03/29)
TMSCl was shown to be an efficient reagent for selective deprotection of the anomeric position protected as N,O-dimethylhydroxylamine glycoside. This deprotection condition was proved to be compatible with a number of protecting groups, such as the TBDPS, acetyl, benzyl, benzylidene, and benzoyl groups.Copyright Taylor and Francis Group, LLC.
