56948-76-6

Basic information

• Product Name: 4-OXO-4-(3-TRIFLUOROMETHYLPHENYL)BUTYRIC ACID
• Synonyms: 4-OXO-4-(3-TRIFLUOROMETHYLPHENYL)BUTYRIC ACID
• CAS NO: 56948-76-6
• Molecular Formula: C₁₁H₉F₃O₃
• Molecular Weight: 246.18
• Mol File: 56948-76-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 340.9°C at 760 mmHg
• Flash Point: 160°C
• Appearance: /
• Density: 1.351g/cm³
• Vapor Pressure: 3.22E-05mmHg at 25°C
• Refractive Index: 1.483
• CAS DataBase Reference: 4-OXO-4-(3-TRIFLUOROMETHYLPHENYL)BUTYRIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-OXO-4-(3-TRIFLUOROMETHYLPHENYL)BUTYRIC ACID(56948-76-6)
• EPA Substance Registry System: 4-OXO-4-(3-TRIFLUOROMETHYLPHENYL)BUTYRIC ACID(56948-76-6)

Safety Data

• Hazardous Substances Data: 56948-76-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H9F3O3/c12-11(13,14)8-3-1-2-7(6-8)9(15)4-5-10(16)17/h1-3,6H,4-5H2,(H,16,17)

Upstream product

• 108-30-5 succinic acid anhydride 
• 98-08-8 α,α,α-trifluorotoluene 

Downstream Products

• 93040-73-4 1-(4-Methyl-piperazin-1-yl)-4-(3-trifluoromethyl-phenyl)-butane-1,4-dione 
• 166312-64-7 N,N-diethyl-4-(3-trifluoromethylphenyl)-4-oxobutanamide 
• 106263-30-3 4,5-dihydro-2-(2-nitrophenyl)-6-<3-(trifluoromethyl)phenyl>-3(2H)-pyridazinone 
• 106263-34-7 2-(2-nitrophenyl)-6-<(3-trifluoromethyl)phenyl>-3(2H)-pyridazinone 
• 106263-40-5 2-(2-aminophenyl)-6-<3-(trifluoromethyl)phenyl>-3(2H)-pyridazinone 
• 106263-45-0 2-<3-(trifluoromethyl)phenyl>pyridazino<1,6-a>benzimidazole 
• 93040-70-1 N-Isopropyl-4-oxo-4-(3-trifluoromethyl-phenyl)-butyramide 
• 93040-69-8 N,N-Dimethyl-4-oxo-4-(3-trifluoromethyl-phenyl)-butyramide 
• 93040-72-3 N-Cyclohexyl-4-oxo-4-(3-trifluoromethyl-phenyl)-butyramide 
• 93040-71-2 N-Isobutyl-4-oxo-4-(3-trifluoromethyl-phenyl)-butyramide 
• 93061-41-7 N-sec-Butyl-4-oxo-4-(3-trifluoromethyl-phenyl)-butyramide 
• 56948-73-3 5-hydroxy-1-methyl-5-(m-trifluoromethylphenyl)pyrrolidone 

Relevant articles and documents

Synthesis of Enantiopure γ-Lactones via a RuPHOX-Ru Catalyzed Asymmetric Hydrogenation of γ-Keto Acids

A RuPHOX?Ru catalyzed asymmetric hydrogenation of γ-keto acids has been developed, affording the corresponding enantiopure γ-lactones in high yields and with up to 97% ee. The reaction could be performed on a gram scale with a relatively low catalyst loading (up to 10000 S/C) under the indicated reaction conditions and the resulting products can be transformed to several enantiopure building blocks, biologically active compounds and enantiopure drugs. (Figure presented.).

SUBSTITUTED THIO-SUBSTITUTED BENZYL-PROPIONYL-L-PROLINES

This disclosure describes novel substituted ω-aroyl(propionyl or butyryl)-L-prolines and the esters and cationic salts thereof which are useful as hypotensive agents in mammals.