56961-16-1

Upstream product

• 610-40-2 3,4-dinitro-chlorobenzene 
• 121-73-3 3-Nitrochlorobenzene 
• 5967-26-0 1,2,4,5-tetranitrobenzene 
• 7664-93-9 sulfuric acid 
• 619-16-9 1-chloro-2,5-dinitrobenzene 
• 7697-37-2 nitric acid 
• 610-26-4 2,4,5-trinitrophenol 

Downstream Products

• 100959-55-5 1-(5-chloro-2,4-dinitro-phenyl)-semicarbazide 
• 2873-62-3 N¹,N³-dimethyl-4,6-dinitrobenzene-1,3-diamine 
• 134282-26-1 picryl-(2,4,5-trinitro-phenyl)-ether 
• 109041-94-3 N-(5-chloro-2,4-dinitro-phenyl)-N'-phenyl-hydrazine 
• 102007-46-5 1,5-dinitro-2,4-bis-p-tolylsulfanyl-benzene 
• 96459-87-9 (5-chloro-2,4-dinitro-phenyl)-p-tolyl sulfide 
• 79236-84-3 1,5-dinitro-2,4-bis(phenylsulfanyl)benzene 
• 98130-54-2 1,5-diazido-2,4-dinitro-benzene 
• 100245-74-7 1-azido-5-chloro-2,4-dinitro-benzene 
• 1210-96-4 1,3-dimethoxy-4,6-dinitrobenzene 
• 57356-27-1 5-chloro-2,4-dinitroanisole 

Relevant academic research and scientific papers

Reactions of Nitrophenols with Phosphorus Oxychloride in Dimethylformamide

A rapid and simple method for the replacement of hydroxyl group of nitrophenols and related compounds by chlorine using phosphorus oxychloride in dimethylformamide at ambient temperature is described.

Nitrocarbons. 4. Reaction of Polynitrobenzenes with Hydrogen Halides. Formation of Polynitrohalobenzenes

Hexanitrobenzene and pentanitrobenzene in benzene solution react with hydrogen halides (HCl, HBr, HI, but not HF) at 25 deg C to produce high yields of pentanitrohalobenzenes and 2,3,4,6-tetranitrohalobenzenes, respectively.Pentanitrofluorobenzene also reacts readily with HCl to yield 3-chloro-2,4,5,6-tetranitrofluorobenzene, but the other pentanitrohalobenzenes are much less reactive. 1,2,3,5- and 1,2,4,5-tetranitrobenzenes react rapidly with concentrated hydrochloric or hydrobromic acids at reflux to form picryl halides and 1-halo-2,4,5-trinitrobenzenes, respectively; pentanitrotoluene reacts very slowly under these conditions to form 3-halo-2,4,5,6-tetranitrotoluenes in lower yields.The scope and limitations of this regioselective reaction are defined, and comparison is made to related reactions.A mechanism is presented and discussed.