619-16-9

Basic information

• Product Name: 2-CHLORO-1,4-DINITROBENZENE
• Synonyms: 2-CHLORO-1,4-DINITROBENZENE;1-Chloro-2,5-dinitrobenzene;1,4-Dinitro-2-chlorobenzene
• CAS NO: 619-16-9
• Molecular Formula: C₆H₃ClN₂O₄
• Molecular Weight: 202.55202
• Mol File: 619-16-9.mol
• Article Data: 3

Chemical Properties

• Melting Point: 64 °C
• Boiling Point: 320.1 °C at 760 mmHg
• Flash Point: 147.4 °C
• Appearance: /
• Density: 1.619 g/cm³
• Vapor Pressure: 0.000607mmHg at 25°C
• Refractive Index: 1.625
• CAS DataBase Reference: 2-CHLORO-1,4-DINITROBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-1,4-DINITROBENZENE(619-16-9)
• EPA Substance Registry System: 2-CHLORO-1,4-DINITROBENZENE(619-16-9)

Safety Data

• Hazard Codes: Xn
• RIDADR: Cool, dry,tightly closed
• Hazardous Substances Data: 619-16-9(Hazardous Substances Data)

Usage

Chemical Properties

Light yellow crystals. Soluble in ethanol and ether; insoluble in water.

Uses

Different sources of media describe the Uses of 619-16-9 differently. You can refer to the following data:
1. Uses are the same as other isomers such as 4-chloro-1,2- dinitrobenzene.
2. 2-?Chloro-?1,?4-?dinitrobenzene is a reagent used in the synthesis of novel thiazole derivatives which are potential coxsackie inhibitors.

InChI:InChI=1/C6H3ClN2O4/c7-5-3-4(8(10)11)1-2-6(5)9(12)13/h1-3H

Upstream product

• 619-18-1 2,5-dinitroaniline 
• 121-87-9 2-Chloro-4-nitroaniline 
• 20607-43-6 sodium isopropanethiolate 
• 13362-35-1 2-chloro-1,4-benzoquinone-4-oxime 
• 36164-93-9 chloro-[1,4]benzoquinone dioxime 
• 7697-37-2 nitric acid 
• 825-41-2 3-chloro-4-nitroaniline 
• 329-71-5 2,5-dinitrophenol 

Downstream Products

• 4920-79-0 2-chloro-4-nitroanisole 
• 121-87-9 2-Chloro-4-nitroaniline 
• 5131-58-8 2,4-diaminonitrobenzene 
• 619-18-1 2,5-dinitroaniline 
• 13059-86-4 2,4-dinitro-N-butylaniline 
• 825-41-2 3-chloro-4-nitroaniline 
• 201413-50-5 N,N'-bis-(2,5-dinitrophenyl)-1,2-diaminoethane 
• 57356-27-1 5-chloro-2,4-dinitroanisole 
• 1210-96-4 1,3-dimethoxy-4,6-dinitrobenzene 
• 1016-90-6 7-nitro-1,2,4-benzotriazin-3-amine 1-oxide 
• 610-31-1 1,2,4-trinitrobenzene 
• 56961-16-1 2,4,5-trinitrochlorobenzene 
• 122834-06-4 2-chloro-5,6-dimethyl-1,4-dinitrocyclohexa-1,3-diene 
• 615-66-7 2-chloro-p-phenylenediamine 

Relevant articles and documents

Aromatic radical anions as possible intermediates in the nucleophilic aromatic substitution (SNAr): An EPR study

The reactions among halonitrobenzenes or polynitrobenzenes and alkoxides, thiolates or tertiary amines have provided the evidence that in a SNAr reaction type a single electron transfer from the nucleophile to the aromatic substrate, to generate two radical species within the solvent cage, can take place to some extent. The detection of radical intermediates by EPR spectroscopy, in several SNAr reactions, is reported.

Reactions of Nitrophenols with Phosphorus Oxychloride in Dimethylformamide

A rapid and simple method for the replacement of hydroxyl group of nitrophenols and related compounds by chlorine using phosphorus oxychloride in dimethylformamide at ambient temperature is described.