56966-47-3Relevant academic research and scientific papers
Microwave assisted rapid synthesis of phenoxazines and benzopyridoxazines
Anchan, Kavitha,Puttappa, Nagaswarupa H.,Poongavanam, Baburajan,Sarkar, Sujit Kumar
, p. 635 - 646 (2020/11/27)
A facile protocol for the synthesis of phenoxazines and benzopyridoxazines by Smiles rearrangement have been demonstrated in short reaction time under microwave irradiation. The control experiments suggest that a reaction proceeds through Smiles rearrangement followed SNAr ring closure by in situ cascade process. In our present work, both the electron donating and electron withdrawing groups were tolerant and provided a corresponding phenoxazine/benzopyridoxazine in good to moderate yields.
Synthesis of Cycloheptatrienes, Oxepines, Thiepines, and Silepines: A Comparison between Br?nsted Acid and Au-Catalysis
Alcarazo, Manuel,Golz, Christopher,Sprenger, Kristin
, p. 6245 - 6254 (2020/10/02)
The cyclization of 1-(benzyl-, oxyaryl-, thioaryl-, and silaaryl)-2-ethynylbenzenes under Br?nsted acid- and Au(I)-catalysis is described. Br?nsted acid catalysis favors without exception the formation of the products derived from the regioselective proto
Pyrazinamide compounds, preparation method and application thereof as well as bactericide
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Paragraph 0143; 0171; 0172, (2018/06/04)
The invention relates to the field of pesticide bactericides and discloses pyrazinamide compounds, a preparation method and an application thereof as well as a bactericide. The compounds have the structure shown in formula (I). The pyrazinamide compounds with the novel structure are designed by introducing pyrazine ring fragments in Pyradiflumid and diphenyl ether fragments with wide bioactivity,and the pyrazinamide compounds can be used as novel SDHIs (succinate dehydrogenase inhibitors) or bactericides.
Design, synthesis and antifungal activity of novel furancarboxamide derivatives
Wen, Fang,Jin, Hong,Tao, Ke,Hou, Taiping
, p. 244 - 251 (2016/05/24)
Twenty-seven novel furancarboxamide derivatives with a diphenyl ether moiety were synthesized and evaluated for their antifungal activity against Rhizoctonia solani, Botrytis cirerea, Valsa Mali and Sphaceloma ampelimum. Antifungal bioassay results indicated that most compounds had good or excellent fungicidal activities for R. solani and S. ampelimum at 20 mg L-1. Among synthesized compounds, compound 18e showed a greater inhibitory effect against S. ampelimum, with half maximal effective concentration (EC50) values of 0.020 mg L-1. This strong activity rivals currently used commercial fungicides, such as Boscalid and Carbendazim, and has great potential as a lead compound for future development of novel fungicides.
DIARYL SUBSTITUTED HETEROAROMATIC COMPOUNDS
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, (2015/01/09)
The invention relates to heterocyclic derivatives, to the use of said derivatives in treating a range of metabolic diseases and other conditions mediated by agonism of the G-protein coupled bile acid GPBAR1/TGR5 receptor, to compositions and formulations containing said derivatives, processes for their preparation and methods of delivery.
Synthesis and enantioselective hydrogenation of seven-membered cyclic imines: Substituted dibenzo[b,f][1,4]oxazepines
Gao, Kai,Yu, Chang-Bin,Li, Wei,Zhou, Yong-Gui,Zhang, Xumu
, p. 7845 - 7847 (2011/09/13)
Highly enantioselective hydrogenation of seven-membered cyclic imines, substituted dibenzo[b,f][1,4]oxazepines, was achieved, with up to 94% ee, by using the [Ir(COD)Cl]2/(S)-Xyl-C3*-TunePhos complex as the catalyst in the presence of morpholine-HCl.
1-,2-,3-,4-,5-,6-,7-,8- AND/OR 9 SUBSTITUTED DIBENZOXAZEPINE COMPOUDS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING PAIN
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, (2008/06/13)
The present invention provides substituted dibenzoxazepine compounds of Formula I: STR1 which are useful as analgesic agents for the treatment of pain, pharmaceutical compositions comprising a therapeutically-effective amount of a compound of Formula I in combination with a pharmaceutically-acceptable carrier, and a method for eliminating or ameliorating pain in an animal comprising administering a therapeutically-effective amount of a compound of Formula I to the animal.
