56966-52-0

Basic information

• Product Name: 5-chloro-2-(2,4-dichlorophenoxy)aniline
• Synonyms: 5-chloro-2-(2,4-dichlorophenoxy)aniline;2,4,4'-Trichloro-2-aminodiphenyl ether;5-chloro-2-(2,4-dichlorophenoxy)-benzenamine
• CAS NO: 56966-52-0
• Molecular Formula: C₁₂H₈Cl₃NO
• Molecular Weight: 288.55702
• EINECS: 260-480-4
• Mol File: 56966-52-0.mol
• Article Data: 4

Chemical Properties

• Melting Point: 67 °C
• Boiling Point: 364.6 °C at 760 mmHg
• Flash Point: 174.3 °C
• Appearance: /
• Density: 1.456 g/cm³
• Vapor Pressure: 1.66E-05mmHg at 25°C
• Refractive Index: 1.642
• PKA: 2.60±0.10(Predicted)
• Water Solubility: 2.6mg/L at 20℃
• CAS DataBase Reference: 5-chloro-2-(2,4-dichlorophenoxy)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-2-(2,4-dichlorophenoxy)aniline(56966-52-0)
• EPA Substance Registry System: 5-chloro-2-(2,4-dichlorophenoxy)aniline(56966-52-0)

Safety Data

• Hazardous Substances Data: 56966-52-0(Hazardous Substances Data)

Usage

Flammability and Explosibility

Nonflammable

InChI:InChI=1/C12H8Cl3NO/c13-7-1-3-11(9(15)5-7)17-12-4-2-8(14)6-10(12)16/h1-6H,16H2

Upstream product

• 611-06-3 2,4-dichloronitrobenzene 
• 583-78-8 2,5-dichlorophenol 
• 120-83-2 2,4-dichlorophenol 
• 100125-34-6 5-chloro-2-(4-chloro-2-nitro-phenoxy)-benzenesulfonyl chloride 
• 89-61-2 2,5-dichloronitrobenzene 
• 2392-48-5 2,4,4'-trichloro-2'-nitrodiphenyl ether 

Downstream Products

• 2172-87-4 2.4.4'-Trichlor-2'-(dimethylamino)-diphenylether 
• 300350-24-7 2,4,4'-trichloro-2'-bromodiphenyl ether 
• 1610840-01-1 (4R)-N-(3-(5-chloro-2-(2,4-dichlorophenoxy)phenylamino)-3-oxopropyl)-2-(4-methoxyphenyl)-5,5-dimethyl-1,3-dioxane-4-carboxamide 
• 1274694-43-7 C₁₃H₁₀Cl₃NO 
• 1422364-63-3 C₁₃H₈Cl₃NO₂ 
• 69206-98-0 5-chloro-2-(2,4-dichloro-phenoxy)-benzoic acid 
• 1422364-65-5 C₁₈H₁₂Cl₃NO₃S 
• 28076-73-5 2,2',4,4'-tetrachlorodiphenylether 
• 47366-42-7 N-[5-Chloro-2-(2,4-dichloro-phenoxy)-phenyl]-C,C,C-trifluoro-methanesulfonamide 

Relevant articles and documents

The hydrogen reduction synthesis of 2, 4, 4 '- trichloro -2' - amino diphenyl ether (by machine translation)

The invention discloses a hydrogenation reduction synthesis of 2, 4, 4 '- trichloro - 2' - amino-diphenyl ether, will be 2, 4, 4 '- trichloro - 2' - nitro-diphenyl ether in a solvent, adding catalyst, dechlorination inhibitors, hydrogen, thermal insulation reaction, after the reaction, the catalyst precipitation separation, synthetic fluid desolution, rectification, to obtain 2, 4, 4 '- trichloro - 2' - diaminodiphenyl ether. The invention hydrogenation after reduction, dechlorination product content can be controlled in a 0.2% the following, through the rectification under a reduction product, the quality of the target product can be obtained. (by machine translation)

A PROCESS FOR THE PREPARATION OF 5-CHLORO-2(2,4-DICHLOROPHENOXY) ANILINE

A novel process for the selective reduction of halonitroarenes in general and halonitroaromatic arenes in particular, without the hydrogenolysis of the C-Cl (where, X represents F-, Cl-, Br- and I) and the C-O-C bonds, in the presence of platinum based catalysts and ammonium formate. The invention makes the use of duel function of ammonium formate, as a hydrogen source for partial reduction (catalytic transfer hydrogenation) and as an additive controlling the hydrogenolysis side reactions during the completion of the reduction by high pressure catalytic hydrogenation using external hydrogen gas source. Uniqueness of the invention lies in the fact that either the catalytic transfer hydrogenation with ammonium formal e or high pressure catalytic hydrogenation in the absence of ammonium formate, when used alone result in lower purity of the said amine. This invention -product is used to synthesize intermediates for making antibacterial compounds.