56966-62-2

Usage

Uses

Used in Organic Synthesis:
1-(4-Bromophenoxy)-2-nitrobenzene is used as a building block in organic synthesis for the creation of various organic compounds. Its unique structure and reactivity make it a valuable component in the development of new chemical entities.
Used in Chemical Research:
In the field of chemical research, 1-(4-Bromophenoxy)-2-nitrobenzene serves as a key intermediate for studying reaction mechanisms and exploring new synthetic pathways.
Used in Pharmaceutical Industry:
1-(4-Bromophenoxy)-2-nitrobenzene is used as a precursor in the synthesis of pharmaceutical compounds. Its properties may contribute to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
1-(4-Bromophenoxy)-2-nitrobenzene may also find use in the agrochemical industry, where it could be employed in the development of new pesticides or other agricultural chemicals.
Used in Materials Science:
1-(4-Bromophenoxy)-2-nitrobenzene's potential applications in materials science include its use in the synthesis of novel materials with specific properties, such as those with enhanced stability or reactivity.
It is important to handle 1-(4-Bromophenoxy)-2-nitrobenzene with care due to its potential hazards to health and the environment. Proper safety measures should be taken during its use and disposal to minimize any risks associated with 1-(4-Bromophenoxy)-2-nitrobenzene.

InChI:InChI=1/C12H8BrNO3/c13-9-5-7-10(8-6-9)17-12-4-2-1-3-11(12)14(15)16/h1-8H

Upstream product

• 2216-12-8 1-nitro-2-phenoxy-benzene 
• 106-41-2 4-bromo-phenol 
• 88-73-3 2-Chloronitrobenzene 
• 23530-43-0 2-(N,N-dimethylaminosulfonyl)nitrobenzene 
• 68574-35-6 4-bromophenyl methanesulfonate 
• 1493-27-2 ortho-nitrofluorobenzene 

Downstream Products

• 70787-31-4 2-amino-2'-bromo-diphenyl ether 
• 56966-46-2 2-(4-bromo-phenoxy)-aniline 
• 72405-05-1 (4-bromo-2-nitro-phenyl)-(2,4-dibromo-phenyl)-ether 
• 204847-20-1 benzoic acid-[2-(4-bromo-phenoxy)-anilide] 
• 858427-74-4 11-(4-cyano-phenyl)-dibenz[b,f][1,4]oxazepine-2-carbonitrile 
• 857542-38-2 4-(2-bromo-dibenz[b,f][1,4]oxazepin-11-yl)-benzonitrile 
• 873977-98-1 acetic acid-[5-bromo-2-(2,4-dibromo-phenoxy)-anilide] 
• 873977-31-2 N-(2-(2-bromophenoxy)-4-bromophenyl)acetamide 
• 860577-49-7 acetic acid-[2-(2,4-dibromo-phenoxy)-anilide] 
• 873386-17-5 acetic acid-[4-bromo-2-(4-bromo-phenoxy)-anilide] 
• 204847-21-2 N-(2-(2-bromophenoxy)phenyl)acetamide 
• 204847-19-8 acetic acid-[2-(4-bromo-phenoxy)-anilide] 
• 187845-86-9 2-(2,4-dibromo-phenoxy)-aniline 
• 873980-35-9 4-bromo-2-(4-bromo-phenoxy)-aniline 

Relevant academic research and scientific papers

Ligand-free copper-catalyzed O-arylation of arenesulfonamides with phenols: An unusual approach to biaryl ether synthesis

An unprecedented ligand-free copper-catalyzed O-arylation of arenesulfonamides with phenols has been developed. Thus, a range of unsysmmetric biaryl ethers were synthesized in excellent yields. The reaction occurs efficiently with excellent regioselectivity through the cleavage of Cary–S bond and with a good tolerance of functional groups on the phenyl ring of phenols. The reaction is appreciated for its readily accessible substrates, mild conditions, and simple operation under air.

Ligand-free solid supported palladium(0) nano/microparticles promoted C-O, C-S, and C-N cross coupling reaction

Ligand-free solid-supported nano and microparticles of Pd(0) (SS-Pd) were used as a heterogeneous catalyst in carbon-heteroatom bond formation reactions. Nitro substituted aryl halides reacted with oxygen, sulfur, and nitrogen nucleophiles to afford the corresponding products in good yields. A one-pot sequential cross coupling and nitro-reduction was also performed using the same SS-Pd catalyst to access amine substituted carbon-heteroatomic molecules. In addition, SS-Pd could be recycled up to seven runs without a significant loss of catalytic activity.

Arylmethanesulfonates are convenient latent phenols in the nucleophilic aromatic substitution reaction

The methanesulfonyl protecting group for a phenol is conveniently unmasked under the conditions of the S(N)Ar reaction with an activated aryl halide, producing diarylether products directly. The method is advantageous when the preparation of a phenol substrate requires O-protection, since the selection of the robust methanesulfonate as a latent phenol obviates a deprotection step prior to the S(N)Ar reaction.