569674-05-1

Basic information

• Product Name: Benzoic acid, 2-(2-methoxy-1-naphthalenyl)-, methyl ester
• CAS NO: 569674-05-1
• Molecular Formula: C19H16O3
• Molecular Weight: 292.334
• Mol File: 569674-05-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-(2-methoxy-1-naphthalenyl)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-(2-methoxy-1-naphthalenyl)-, methyl ester(569674-05-1)
• EPA Substance Registry System: Benzoic acid, 2-(2-methoxy-1-naphthalenyl)-, methyl ester(569674-05-1)

Safety Data

• Hazardous Substances Data: 569674-05-1(Hazardous Substances Data)

Upstream product

• 93-04-9 2-Methoxynaphthalene 
• 134-20-3 2-carbomethoxyaniline 
• 610-96-8 methyl chlorobenzoate 
• 17212-97-4 2-(2-methoxynaphth-1-yl)-2-propanol 
• 36321-90-1 2-methoxy-1-naphthylmagnesium bromide 

Downstream Products

• 101736-66-7 2-(2-methoxy-[1]naphthyl)-benzoic acid 

Relevant articles and documents

Palladium-catalyzed arylation of α,α-disubstituted arylmethanols via cleavage of a C-C or a C-H bond to give biaryls

The palladium-catalyzed arylation of α,α-disubstituted arylmethanols with aryl halides proceeds not only via C-H bond cleavage at the ortho-position, but also via cleavage of the sp2-sp3 C-C bond with the liberation of ketones (β-carbon elimination) to give the corresponding biaryls. Both reactions appear to occur through common arylpalladium(II) alcoholate intermediates. The results of systematic studies with respect to which C-C or C-H bond is preferentially cleaved in the arylation are reported. Among the important findings is the selective elimination of ortho-substituted aryl groups even from aryl(diphenyl)methanols due to steric reasons. Thus, various biaryls having ortho-substituents can be produced efficiently by treatment of the corresponding aryl(diphenyl or dimethyl)methanols with aryl bromides and chlorides.