569686-36-8Relevant academic research and scientific papers
MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE
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Paragraph 001028, (2019/03/05)
The present disclosure provides for compounds of Formula (I) wherein A2, A3, A4, A6, A7, A8, A15, RA, R5, R9, R10A, R10B, R11, R12, R13, R14, R16, W, X, and Y have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including cancer. Also provided are pharmaceutical compositions comprising compounds of Formula (I).
Asymmetric Horner-Wadsworth-Emmons reaction utilizing isomannide and isosorbide derivatives as chiral auxiliaries
Sano, Shigeki,Teranishi, Rie,Nakano, Fumihito,In, Kyougetu,Takeshige, Hiroe,Ishii, Takahiro,Shiro, Motoo,Nagao, Yoshimitsu
, p. 793 - 804 (2007/10/03)
The diastereoselective Horner-Wadsworth-Emmons reaction of chiral phosphonates with σ-symmetric 4-tert-butylcyclohexanone and 4-phenylcyclohexanone was investigated by employing isomannide and isosorbide derivatives as chiral auxiliaries. α-Fluoro-α,β-uns
