57003-57-3

Basic information

• Product Name: (R)-2-((S)-Hydroxy-phenyl-methyl)-3-methyl-but-3-enoic acid ethyl ester
• CAS NO: 57003-57-3
• Molecular Weight: 234.295
• Mol File: 57003-57-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (R)-2-((S)-Hydroxy-phenyl-methyl)-3-methyl-but-3-enoic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-((S)-Hydroxy-phenyl-methyl)-3-methyl-but-3-enoic acid ethyl ester(57003-57-3)
• EPA Substance Registry System: (R)-2-((S)-Hydroxy-phenyl-methyl)-3-methyl-but-3-enoic acid ethyl ester(57003-57-3)

Safety Data

• Hazardous Substances Data: 57003-57-3(Hazardous Substances Data)

Upstream product

• 111042-64-9 3-methyl(tri-n-butyltin)crotonate 
• 100-52-7 benzaldehyde 
• 111042-66-1 ethyl 3-methyl-4-(trichlorostannyl)-2-butenoate 
• 92511-62-1 ethyl 3-methyl-4-(tributylstannyl)-2-butenoate 
• 111070-61-2 ethyl 4-(chlorodibutylstannyl)-3-methyl-2-butenoate 
• 111042-65-0 ethyl 4-(butyldichlorostannyl)-3-methyl-2-butenoate 

Downstream Products

• 69637-31-6 (R)-2-((S)-Hydroxy-phenyl-methyl)-3-methyl-but-3-enoic acid 

Relevant articles and documents

Stabilization and activation of dienolates with germanium and tin. Stero- and regioselective aldol reactions, regioselective coupling reactions, and regioselective synthesis of amino acid derivatives

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Diastereo- and Regio-selective Aldol Condensation by Trapping Dienolates with Tin

Although the reaction of dienolate (1) with aldehydes is frequently lacking in regio- and diastereo-selectivity, the γ-tin substituted derivatives (5), easily obtainable from (1), give (3) and (4) diastereoselectively by controlling the reaction conditions.