57013-02-2Relevant academic research and scientific papers
Iterative synthesis of alkenes by insertion of lithiated epoxides into boronic esters
Bojaryn, Kevin,Fritsch, Stefan,Hirschhaüser, Christoph
supporting information, p. 2218 - 2222 (2019/04/10)
The insertion of lithiated epoxides into boronic esters followed by thermal syn-elimination provides a stereospecific entry to alkenes. This process avoids transition metals and is amenable to iteration to provide higher substitution patterns.
Stereoselectivity of the Thermally Initiated Free-Radical Chain Addition of Cyclohexane to 1-Alkynes
Metzger, Juergen O.,Blumenstein, Michael
, p. 2493 - 2500 (2007/10/02)
Alkanes can be added to alkynes in a thermally initiated free-radical chain reaction ("ane reaction").The addition of cyclohexane to 1-alkynes 1a-l yields a mixture of (Z)- and (E)-2-cyclohexyl-1-alkenes 3a-l.An essential step in this reaction is the addi
Stereoselective Synthesis of Unhindered Olefins by 2-Fold Extrusion Reactions
Collazo, Luis R.,Guziec, Frank S.
, p. 43 - 46 (2007/10/02)
Two-fold extrusion reactions of 1,3,4-thiadiazolines 1 provide a convenient stereoselective route to unhindered Z-olefins.An improved preparation of the thiadiazolines involves reaction of an aldehyde with H2S-hydrazine, followed by in situ oxidation of the intermediate predominantly trans thiadiazolidine 2.Stereospecific extrusion of nitrogen yields the cis-thiirane which upon treatment with triphenylphosphine affords the corresponding Z-alkene in good yields.
A FACILE REDUCTIVE CLEAVAGE OF ALLYLIC AND BENZYLIC ESTERS WITH LOW VALENT TITANIUM REAGENTS
Satyanarayana, K.,Chidambaram, N.,Chandrasekaran, S.
, p. 2159 - 2166 (2007/10/02)
The reaductive cleavage of allylic and benzylic esters 1a-g with titanium(II) reagent derived from Mg/Hg-TiCl4 yielded the corresponding acids 3a-g and dimeric hydrocarbons 2a-g under mild reaction conditions.
