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1-Piperazinecarboxylic acid, 4-[2-fluoro-4-(methoxycarbonyl)phenyl]-, 1,1-dimethylethyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 570408-10-5 Structure
  • Basic information

    1. Product Name: 1-Piperazinecarboxylic acid, 4-[2-fluoro-4-(methoxycarbonyl)phenyl]-, 1,1-dimethylethyl ester
    2. Synonyms: tert-butyl 4-[2-fluoro-4-(methoxycarbonyl)phenyl]piperazine-1-carboxylate;tert-butyl 4-(2-fluoro-4-(methoxycarbonyl)phenyl)piperazine-1-carboxylate;
    3. CAS NO:570408-10-5
    4. Molecular Formula: C17H23FN2O4
    5. Molecular Weight: 338.379
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 570408-10-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 454.0±45.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: 1.199±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1-Piperazinecarboxylic acid, 4-[2-fluoro-4-(methoxycarbonyl)phenyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-Piperazinecarboxylic acid, 4-[2-fluoro-4-(methoxycarbonyl)phenyl]-, 1,1-dimethylethyl ester(570408-10-5)
    11. EPA Substance Registry System: 1-Piperazinecarboxylic acid, 4-[2-fluoro-4-(methoxycarbonyl)phenyl]-, 1,1-dimethylethyl ester(570408-10-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 570408-10-5(Hazardous Substances Data)

570408-10-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 570408-10-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,7,0,4,0 and 8 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 570408-10:
(8*5)+(7*7)+(6*0)+(5*4)+(4*0)+(3*8)+(2*1)+(1*0)=135
135 % 10 = 5
So 570408-10-5 is a valid CAS Registry Number.

570408-10-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-(2-fluoro-4-methoxycarbonylphenyl)piperazine-1-carboxylic acid tert-butyl ester

1.2 Other means of identification

Product number -
Other names tert-butyl 4-[2-fluoro-4-(methoxycarbonyl)phenyl]piperazine-1-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:570408-10-5 SDS

570408-10-5Relevant articles and documents

NON BRAIN PENETRANT A2A INHIBITORS AND METHODS FOR USE IN THE TREATMENT OF CANCERS

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Paragraph 1762; 1764, (2020/04/24)

The present invention relates to compounds of Formula (I) or pharmaceutically acceptable salts thereof. The invention further relates to the use of the compounds of Formula (I) as A2A inhibitors. The invention also relates to the use of the compounds of F

MODULATORS OF ESTROGEN RECEPTOR PROTEOLYSIS AND ASSOCIATED METHODS OF USE

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Paragraph 00460, (2018/08/20)

The present disclosure relates to bifunctional compounds, which find utility as modulators of estrogen receptor (target protein). In particular, the present disclosure is directed to bifunctional compounds, which contain on one end a cereblon, Von Hippel-Lindau ligase-binding moiety, Inhibitors of Apotosis Proteins, or mouse double-minute homolog 2 ligand, which binds to the respective E3 ubiquitin ligase, and on the other end a moiety which binds the target protein, such that the target protein is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of target protein. The present disclosure exhibits a broad range of pharmacological activities associated with degradation/inhibition of target protein. Diseases or disorders that result from aggregation or accumulation of the target protein are treated or prevented with compounds and compositions of the present disclosure.

New isoxazolidinone and 3,4-dehydro-β-proline derivatives as antibacterial agents and MAO-inhibitors: A complex balance between two activities

Ferrazzano, Lucia,Viola, Angelo,Lonati, Elena,Bulbarelli, Alessandra,Musumeci, Rosario,Cocuzza, Clementina,Lombardo, Marco,Tolomelli, Alessandra

, p. 906 - 919 (2016/09/28)

Among the different classes of antibiotics, oxazolidinone derivatives represent important drugs, since their unique mechanism of action overcomes commonly diffused multidrug-resistant bacteria. Anyway, the structural similarity of these molecules to monoa

Poly (ADP-Ribose) Polymerase (PARP) Inhibitors

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Page/Page column 106-107, (2010/08/07)

Disclosed are compounds of the following formula: in which R1, R2, R3, R4, R5, R6, R7, X, and t are defined in the specification. Also disclosed are pharmaceutical compositions, kits, and articles of manufacture, which contain the compounds, methods and intermediates useful for making the compounds, and methods of using the compounds to treat diseases, disorders, and conditions related to PARP activity.

POLY (ADP-RIBOSE) POLYMERASE (PARP) INHIBITORS

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Page/Page column 184, (2010/11/04)

Compounds of the following formula are provided for use in inhibiting Poly (ADP-ribose) Polymerase (PARP): wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds,

PIPERAZINYL DERIVATIVES USEFUL AS MODULATORS OF THE NEUROPEPTIDE Y2 RECEPTOR

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Page/Page column 80, (2009/07/18)

The present invention is directed to piperidinyl and piperazinyl derivatives of formula (I) useful as inhibitors of the NPY Y2 receptor, pharmaceutical compositions comprising said compounds, processes for the preparation of said compounds and the use of

2-ACYLAMINOTHIAZOLE DERIVATIVE OR SALT THEREOF

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Page/Page column 17, (2010/11/08)

2-Acylaminothiazole derivatives or salts thereof which have a platelet increasing activity based on an excellent human c-mpl-Ba/F3 cell growth function and a function of accelerating formation of megakaryocytic colonies and which are useful for treating thrombocytopenia are provided.

2-ACYLAMINOTHIAZOLE DERIVATIVE OR SALT THEREOF

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Page 22; 26, (2010/02/08)

A 2-acylaminothiazole derivative or a pharmaceutically acceptable salt thereof having an excellent effect of proliferating human c-mpl-Ba/F3 cells and an activity of increasing platelets based on the effect of promoting the formation of megakaryocytic colonies. A compound or a pharmaceutically acceptable salt thereof useful in treating thrombocytopenia.

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