57045-39-3

Upstream product

• 23973-65-1 2-cyano-benzylphosphonic acid diethyl ester 
• 66-99-9 β-naphthaldehyde 
• 100-47-0 benzonitrile 
• 40231-00-3 trimethyl(2-(naphthalen-2-yl)ethynyl)silane 
• 2949-26-0 2-ethynylnaphthalene 
• 825-60-5 benzimidic acid ethyl ester 

Relevant academic research and scientific papers

Manganese-Catalyzed ortho-C?H Alkenylation of Aromatic N?H Imidates with Alkynes: Versatile Access to Mono-Alkenylated Aromatic Nitriles

So far, the direct C?H alkenylation of aromatic nitriles with alkynes has not been achieved. Herein, we discribe the first manganese-catalyzed C?H alkenylation of aromatic N?H imidates to access mono-alkenylated aromatic nitriles. The reaction is accelerated by the presence of a catalytic amount of sodium pivalate. This protocol is also highlighted by the simple catalytic system, good compatibility of functional groups, and excellent mono-/dialkenylation selectivity as well as E/Z stereoselectivity. (Figure presented.).

Olefin-Oxazolines (OlefOx): Highly modular, easily tunable ligands for asymmetric catalysis

Figure presented Foxy ligands: An efficient three-step synthesis allows the new highly modular family of olefin-oxazoline ligands (OlefOx; see picture) to be exploited in asymmetric catalysis. The ease of electronic and steric variation and the successful