23973-65-1Relevant articles and documents
DICYANSTYRYL BENZENE DERIVATIVES AND FLUORESCENT MATERIAL COMPRISING THE SAME
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, (2019/06/13)
The present invention refers to die [...] benzene derivatives represented by formula 1 are disclosed. The, head of the present invention die [...] benzene to yield fluorescent derivatives (Dicyanstyryl benzene) to minimize environmental pollution by reducing the drain diameter number fluorescent material can be [...] number can be improve. [Formula 1] (by machine translation)
Green synthesis method of 1,4-bis(2-cyanostyryl)benzene
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Page/Page column 3; 6; 7; 8, (2018/03/01)
The invention discloses a green synthesis method of 1,4-bis(2-cyanostyryl)benzene, and belongs to the technical field of chemical synthesis. The green synthesis method comprises the following steps: adding excessive amount of triethyl phosphite and a solvent into a reactor under the normal pressure, heating, rapidly stirring an added dissolved cyanobenzylchloride solution, continuing to add the material, and conducting a thermal reaction to obtain a reactant; adding N,N-dimethylformamide (DMF) into the reactant, dissolving, stirring, respectively adding terephthalaldehyde and an alkali at equal molar weight, conducting a thermal reaction, cooling, regulating the PH value, cooling, centrifuging, refining with methyl alcohol, drying under the negative pressure, and pulverizing to obtain 1,4-bis(2-cyanostyryl)benzene; and centrifuging a mother solution, and distilling to obtain sodium diethylphosphate. The green synthesis method overcomes the defects of excessive phosphorus containing wastes, difficulty in separating and processing and the like, the production of sodium dihydrogen phosphate and other phosphorus containing wastes is greatly reduced, and sodium diethylphosphate having the industrial application value is achieved with the high yield.
Ligustrazine Derivatives. Part 4: Design, Synthesis, and Biological Evaluation of Novel Ligustrazine-based Stilbene Derivatives as Potential Cardiovascular Agents
Deng, Lijuan,Guo, Xiuli,Zhai, Li,Song, Yuning,Chen, Hongfei,Zhan, Peng,Wu, Jingde,Liu, Xinyong
experimental part, p. 731 - 739 (2012/05/20)
A series of novel stilbene derivatives containing ligustrazinyl moiety was designed, synthesized, and assayed for their protective effects on damaged endothelial cells. The results showed that most ligustrazinyl stilbene derivatives exhibited high protective effects on the human umbilical vascular endothelial cells (HUVECs) damaged by hydrogen peroxide in comparison with Ligustrazine. The stilbene derivatives A6, A9, A11, A21, A24, A25, and A27 exhibited high potency with low EC50 values ranged from 0.0249μm to 0.0898mm. Compound A27 displayed EC50 0.0249μm, which is 30000 times higher than that of Ligustrazine, presenting a most promising lead for further investigation. Structure-activity relationships were briefly discussed.