57061-25-3Relevant academic research and scientific papers
Cationic gold(I)-mediated intramolecular cyclization of 3-alkyne-1,2-diols and 1-amino-3-alkyn-2-ols: A practical route to furans and pyrroles
Egi, Masahiro,Azechi, Kenji,Akai, Shuji
supporting information; experimental part, p. 5002 - 5005 (2009/12/26)
The intramolecular cyclizations of the 3-alkyne-1,2-diols and the 1-amlno-3-alkyn-2-ols with a low catalyst loading (0.05-0.5 mol %) of (Ph 3P)AuCl - AgNTf2 or (Ph3P)AuCl-AgOTf proceeded at room temperature to provide a variety of substituted furans and pyrroles In excellent yields (85-98% yields). This method Is also fully applicable to the conversion of several dozen grams of the substrate using only 0.05 mol % each of the Au and Ag catalysts.
Regioselective ortho lithiation of 3-aryl and 3-styryl furans
Tofi, Maria,Georgiou, Thomas,Montagnon, Tamsyn,Vassilikogiannakis, Georgios
, p. 3347 - 3350 (2007/10/03)
(Chemical Equation Presented) An unusual regioselectivity pattern for the ortho lithiation of 3-aryl and 3-styryl furans has been uncovered wherein lithiation occurs preferentially at the sterically encumbered 2-position. The results are attributed, at le
Synthesis and insect antifeedant activity of 2-substituted 2,3- dihydrofuran-3-ols and butenolides (Part II)
Klein Gebbinck, Edwin A.,Stork, Gerrit A.,Jansen, Ben J. M.,De Groot, Aede
, p. 11077 - 11094 (2007/10/03)
The introduction of a hydroxy group at C-13 of the clerodane skeleton is proposed as a strategy to potentially increase the antifeedant activity of simple analogs. This idea is applied to clerodane analogs with furan or butenolide type sidechains and ther
