571168-96-2Relevant academic research and scientific papers
A synthetic entry to furo[2,3-b]pyridin-4(1H)-ones and related furoquinolinones via iodocyclization
Aillaud, Isabelle,Bossharth, Emmanuel,Conreaux, David,Desbordes, Philippe,Monteiro, Nuno,Balme, Genevieve
, p. 1113 - 1116 (2007/10/03)
N-Methyl-4-alkoxy-3-alkynylpyridin-2(1H)-ones readily undergo iodine-promoted 5-endo-heteroannulation under mild conditions to 3-iodofuropyridinium triiodide salts in moderate to good yields. The latter may be dealkylated in situ upon exposure to an iodid
Palladium-mediated three-component synthesis of furo[2,3-b]pyridones by one-pot coupling of 3-lodopyridones, alkynes, and organic halides
Bossharth, Emmanuel,Desbordes, Philippe,Monteiro, Nuno,Balme, Genevieve
, p. 2441 - 2444 (2007/10/03)
(Matrix presented) The one-pot assembly of 4-alkoxy-3-iodo-2-pyridones, terminal alkynes, and organic halides has been achieved by integration of two sequential palladium-mediated cross-coupling reactions - Sonogashira and Wacker-type heteroannulation pro
