571200-57-2Relevant academic research and scientific papers
Carbapenem biosynthesis: Confirmation of stereochemical assignments and the role of CarC in the ring stereoinversion process from L-Proline
Stapon, Anthony,Li, Rongfeng,Townsend, Craig A.
, p. 8486 - 8493 (2003)
(5R)-Carbapen-2-em-3-carboxylic acid is the simplest structurally among the naturally occurring carbapenem β-lactam antibiotics. It co-occurs with two saturated (3S,5S)- and (3S,5R)-carbapenam carboxylic acids. Confusion persists in the literature about t
Convenient syntheses of (3S,5S)-carbapenam-3-carboxylates and their biosynthetic relevance
Bycroft, Barrie W.,Chhabra, Siri Ram,Kellam, Barrie,Smith, Paul
, p. 973 - 976 (2007/10/03)
Starting from readily available glutamate derivatives, facile stereoselective syntheses of (3S,5S)-carbapenam-3-carboxylates have been developed. Their significance in confirming the absolute configuration of the natural material is discussed.
