571923-85-8

Basic information

• Product Name: 1,3-benzodioxol-5-yl 3,4,5-trimethoxybenzoate
• Synonyms: 1,3-benzodioxol-5-yl 3,4,5-trimethoxybenzoate
• CAS NO: 571923-85-8
• Molecular Formula: C17H16O7
• Molecular Weight: 332.30474
• Mol File: 571923-85-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,3-benzodioxol-5-yl 3,4,5-trimethoxybenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-benzodioxol-5-yl 3,4,5-trimethoxybenzoate(571923-85-8)
• EPA Substance Registry System: 1,3-benzodioxol-5-yl 3,4,5-trimethoxybenzoate(571923-85-8)

Safety Data

• Hazardous Substances Data: 571923-85-8(Hazardous Substances Data)

Upstream product

• 533-31-3 Sesamol 
• 4521-61-3 3,4,5-Trimethoxybenzoyl chloride 
• 118-41-2 Eudesmic acid 

Relevant articles and documents

Synthesis, evaluation, and molecular docking studies of cycloalkyl/aryl-3,4,5-trimethylgallates as potent non-ulcerogenic and gastroprotective anti-inflammatory agents

In our effort to identify the effective gastric sparing and protective anti-inflammatory agents, a series of cycloalkyl/aryl-3,4,5-trimethylgallates were synthesized and characterized. The physicochemical properties were studied to assess the lipophilicity and chemical stability. Subsequently, the compounds were evaluated for their anti-inflammatory activity and effect on gastric mucosa by most active compounds. All the compounds exhibited promising anti-inflammatory activity. In particular, 4a, 4b, 4g, and 4h emerged as the most active compounds in the series. The results of gastric mucosal studies and biochemical estimations suggested that these compounds are non-ulcerogenic and gastroprotective. The molecular docking analysis was performed to understand the binding interactions of these compounds to cyclooxygenase isoenzyme (COX-1 and COX-2). The results from this investigation suggests cycloalkyl/aryl-3,4,5- trimethylgallates as potent safer gastrosparing and protective anti-inflammatory agents.